Etravirine (TMC125)

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Names

[ CAS No. ]:
269055-15-4

[ Name ]:
Etravirine (TMC125)

[Synonym ]:
Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-
etravirine
4-({6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl}oxy)-3,5-dimethylbenzonitrile
tmc 125

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
637.4±65.0 °C at 760 mmHg

[ Melting Point ]:
265ºC (dec.)

[ Molecular Formula ]:
C20H15BrN6O

[ Molecular Weight ]:
435.277

[ Flash Point ]:
339.3±34.3 °C

[ Exact Mass ]:
434.049072

[ PSA ]:
120.64000

[ LogP ]:
4.19

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.703

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • etravirine phosphate
  • Etravirine-d6
  • Etravirine D4
  • Dihydroxy Etravirine
  • Monohydroxy Etravirine
  • 4-({6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl}oxy)-3 ,5-dimethylbenzonitrile hydrobromide (1:1)