3,4-Difluorophenol

Names

[ Name ]:
3,4-Difluorophenol

[Synonym ]:
MFCD00010315
Phenol, 3,4-difluoro-
3,4-Difluor-phenol
EINECS 424-300-1
QR CF DF
3,4-Difluorophenol
Phenol,3,4-difluoro
3,4-difluoro phenol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
184.6±0.0 °C at 760 mmHg

[ Melting Point ]:
34-38 °C(lit.)

[ Molecular Formula ]:
C₆H₄F₂O

[ Molecular Weight ]:
130.092

[ Flash Point ]:
57.8±0.0 °C

[ Exact Mass ]:
130.023026

[ PSA ]:
20.23000

[ LogP ]:
2.13

[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.496

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H302 + H312-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R11;R20/21/22;R34

[ Safety Phrases ]:
S26-S36-S45-S36/37/39-S16

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
4.1

[ HS Code ]:
29081000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

4-(3,4-Difluorophenoxy)benzaldehyde
1,2-DIFLUORO-4-ISOPROPOXYBENZENE
1,2-Difluoro-4-methoxy-5-nitrobenzene
5,6-Difluoro-o-anisaldehyde
4,5-Difluoro-2-nitrophenol
4-Fluoro-3-methoxyphenol
1,2-Difluoro-4-methoxybenzene
2-carboxyethyl acrylate
3-(3,4-difluorophenoxy)propanoic acid
2-(3,4-difluorophenoxy)acetic acid

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Transformation of difluorinated phenols by Penicillium frequentans Bi 7/2.

Biodegradation 8(6) , 379-85, (1997)

The Penicillium frequentans strain Bi 7/2, using phenol as a sole source of carbon and energy, transformed the fluorinated phenols 2,3-, 2,4-, 2,5- and 3,4-difluorophenol rapidly. After growth on phen...