3-(Tritylthio)propionic acid

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Names

[ CAS No. ]:
27144-18-9

[ Name ]:
3-(Tritylthio)propionic acid

[Synonym ]:
3-(Tritylsulfanyl)propanoic acid
3-[(triphenylmethyl)thio]propionic acid
(Trt)-S-(CH2)2-COOH
S-Trityl-3-Mercaptopropionic Acid
3-(tritylthio)propanoic acid
3-(Tritylthio)propionic acid
MFCD00237291
mpa(trt)-oh
Trt-SCH2CH2CO2H
Propanoic acid, 3-[(triphenylmethyl)thio]-
3-Tritylmercapto-Propionicacid
Trt-S-CH2-CH2-COOH
Mpa(Trt)

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
503.8±38.0 °C at 760 mmHg

[ Melting Point ]:
211-213°C

[ Molecular Formula ]:
C22H20O2S

[ Molecular Weight ]:
348.458

[ Flash Point ]:
258.5±26.8 °C

[ Exact Mass ]:
348.118408

[ PSA ]:
62.60000

[ LogP ]:
5.64

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.626

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H413

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Precursor & DownStream

Precursor

  • Triphenylmethyl Chloride
  • 3-Mercaptopropionic acid
  • Tritanol
  • 3-Bromopropanoic acid
  • Tritylthiol

DownStream

  • Tritanol
  • Acm-thiopropionic acid
  • Mpa(Trt)-OSu
  • 1-methyl-1,3,3-triphenyl-2H-indene
  • Triphenylmethane

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Cancer cell surface induced peptide folding allows intracellular translocation of drug.

J. Control. Release 209 , 317-26, (2015)

Many lead molecules identified in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. These orphaned molecules could have clinical value if sol...


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Related Compounds

  • 3-propionic acid
  • 3-propionic acid 2,4,5-trichlorophenyl ester
  • Indole-3-propionic acid,-alpha--mercapto-, DL- (8CI)
  • indole-3-propionic acid chloride
  • (R)-methyl 2-(5-bromopentanamido)-3-(tritylthio)propanoate
  • S-trityl-L-cysteine methyl ester