Neoandrographolide

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Names

[ Name ]:
Neoandrographolide

[Synonym ]:
2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-
neo-Andrographolide
{(1R,4aS,5R,8aS)-1,4a-Dimethyl-6-methylene-5-[2-(2-oxo-2,5-dihydrofuran-3-yl)ethyl]decahydronaphthalen-1-yl}methyl β-D-glucopyranoside
{(1R,4aS,5R,8aS)-1,4a-Dimethyl-6-methylene-5-[2-(2-oxo-2,5-dihydro-3-furanyl)ethyl]decahydro-1-naphthalenyl}methyl β-D-glucopyranoside
neoandrographoside
Neoandrographolid
ANDROGRAPHOLIDE,NEO

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
668.1±55.0 °C at 760 mmHg

[ Melting Point ]:
167-168ºC

[ Molecular Formula ]:
C₂₆H₄₀O₈

[ Molecular Weight ]:
480.591

[ Flash Point ]:
220.1±25.0 °C

[ Exact Mass ]:
480.272308

[ PSA ]:
125.68000

[ LogP ]:
2.11

[ Vapour Pressure ]:
0.0±4.6 mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
2-8C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata.

Biochem. Pharmacol. 46(1) , 182-5, (1993)

The diterpenes andrographolide (I), andrographiside (II) and neoandrographolide (III) isolated from Andrographis paniculata were investigated for their protective effects on hepatotoxicity induced in ...

Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression.

Int. Immunopharmacol. 10(11) , 1361-73, (2010)

In inflammation, the responses to noxious stimuli are controlled by the highly modulated interactions between various immune cells and chemical mediators. The purpose of this study is to evaluate and ...

Quantitative analysis of four major diterpenoids in Andrographis paniculata by 1H NMR and its application for quality control of commercial preparations.

J. Pharm. Biomed. Anal. 70 , 87-93, (2012)

A quantitative proton nuclear magnetic resonance technique (qHNMR) has been successfully introduced to quantify andrographolide, dehydroandrographolide, deoxyandrographolide and neoandrographolide in ...

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