Benzamide,N,N-diethyl-2-methyl-

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Names

[ CAS No. ]:
2728-04-3

[ Name ]:
Benzamide,N,N-diethyl-2-methyl-

[Synonym ]:
o-toluic acid diethylamide
2-Methyl-N,N-diethylbenzamide
o-DETA
o-DEET
N,N-diethyl-2-toluamide
N,N-diethyl ortho-toluamide
Benzamide,N,N-diethyl-2-methyl
N,N-diethyl-2-methyl-benzamide
N,N-Diethyl-o-toluamide

Chemical & Physical Properties

[ Density]:
0.985g/cm3

[ Boiling Point ]:
316.7ºC at 760mmHg

[ Molecular Formula ]:
C12H17NO

[ Molecular Weight ]:
191.26900

[ Flash Point ]:
139.8ºC

[ Exact Mass ]:
191.13100

[ PSA ]:
20.31000

[ LogP ]:
2.47700

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XS3850000
CHEMICAL NAME :
o-Toluamide, N,N-diethyl-
CAS REGISTRY NUMBER :
2728-04-3
BEILSTEIN REFERENCE NO. :
2257532
LAST UPDATED :
199707
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H17-N-O
MOLECULAR WEIGHT :
191.30
WISWESSER LINE NOTATION :
2N2&VR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,97,1959
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,97,1959 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1210 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,772,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
52500 mg/kg/30W-C
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,772,1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1410 No. of Facilities: 180 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 4511 (estimated)

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Iodotoluene
  • carbon monoxide
  • Diethylamine
  • O-Toluoylchloride
  • N-dichlorophosphinothioyl-N-ethylethanamine
  • 2-Methylbenzaldehyde
  • N,N-DIETHYLBENZAMIDE
  • methyl iodide
  • 2-Methylbenzoic acid
  • 2-Chlorotoluene

DownStream

  • 3-(2-hydroxyphenyl)-2H-isoquinolin-1-one
  • 3,4-Dihydronaphthalen-1(2H)-one
  • Methyl o-methylbenzoate
  • indeno[2,1-b]chromene-6,11-dione
  • N,N-diethyl-2-(hydroxymethyl)benzamide
  • 3-Phenyl-3,4-dihydroisoquinolin-1(2H)-one
  • 1H-2-Benzopyran-1-one,3,4-dihydro-3-phenyl-
  • 3-(4-methoxyphenyl)isochromen-1-one
  • 3-METHYL-ISOCHROMEN-1-ONE
  • 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • Benzamide,N,N-diethyl-2-methyl-6-(trimethylsilyl)
  • DIETHYL TOLUAMIDE
  • Benzamide, N,N-diethyl-2,3-dihydroxy- (9CI)
  • Benzamide,N,N-diethyl-2-methoxy-
  • BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-
  • Benzamide,N,N-diethyl-2-hydroxy-
  • 2,2-Dimethylbut-3-yn-1-amine hydrochloride
  • 3-Amino-5-(sulfanylmethyl)benzaldehyde
  • (9H-fluoren-9-yl)methyl 4-{3-[(fluorosulfonyl)methyl]-5-iodophenyl}piperazine-1-carboxylate
  • 3-Amino-5-[(piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride
  • (9H-fluoren-9-yl)methyl 4-[3-(azidomethyl)-2-methyl-5-sulfanylphenyl]piperazine-1-carboxylate
  • 2-({[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methoxy-2-oxoethyl)-2-methylphenyl]methyl}amino)acetic acid
  • 2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-(2-methoxy-2-oxoethyl)-2-methylphenyl]methoxy}acetic acid
  • tert-butyl N-[1-amino-3-(2,3-dihydro-1-benzofuran-5-yl)propan-2-yl]carbamate
  • Tert-butyl 4-{[3-iodo-4-methyl-5-(piperazin-1-yl)phenyl]methyl}piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-[5-(fluorosulfonyl)-2-methyl-3-[(piperazin-1-yl)methyl]phenyl]carbamate
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