PhTX-433

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Names

[ CAS No. ]:
276684-27-6

[ Name ]:
PhTX-433

[Synonym ]:
(S)-N-[4-[[3-[(3-Aminopropyl)amino]propyl]amino]butyl]-4-hydroxy-|A-[(1-oxobutyl)amino]benzenepropanamide tris(trifluoroacetate) salt
Philanthotoxin 433 tris(trifluoroacetate) salt
PhTX-433 tris(trifluoroacetate) salt

Chemical & Physical Properties

[ Molecular Formula ]:
C29H44F9N5O9

[ Molecular Weight ]:
777.67300

[ Exact Mass ]:
777.30000

[ PSA ]:
247.39000

[ LogP ]:
6.09670

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 2811 6.1/PG 2

Articles

Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.

Eur. J. Pharmacol. 228 , 201-206, (1992)

A synthetic analog of philanthotoxin-433, philanthotoxin-343 (PhTX-343), was tested in hippocampal pyramidal neurons in vitro. PhTX-343 (2 microM) did not significantly change synaptic transmission me...

Philanthotoxin inhibits Ca2+ currents in rat hippocampal CA1 neurons.

Eur. J. Pharmacol. 270 , 357-360, (1994)

The wasp venom philanthotoxin-4.3.3 (PhTX-4.3.3) is an antagonist of glutamate transmission in the insect as well as in the mammalian brain. It was recently shown that PhTX-4.3.3 inhibits the N-methyl...

Inhibition of dipteran larval neuromuscular synaptic transmission by analogues of philanthotoxin-4.3.3: a structure-activity study.

Comp. Biochem. Physiol. 102C , 267-272, (1992)

1. The blocking action of delta-philanthotoxin (PhTX-4.3.3), a wasp toxin composed of a polyamine chain, an aromatic amino acid (tyrosyl) nucleus and an aliphatic (butanoic) acid was studied, together...


More Articles

Related Compounds

  • PhTX-433
  • SM-433
  • 2-((((4,6-Bis(bis(methoxymethyl)amino)-1,3,5-triazin-2-yl)(methoxymethyl)amino)methyl)amino)-9-methoxy-1H-xantheno(2,1,9-def)isoquinoline-1,3(2H)-dione
  • Philanthotoxin 343
  • duolite(r) c 433, 4.2 meq/ml
  • Philanthotoxin-7,4 (PhTx-74)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 9-Azaspiro[bicyclo[3.3.1]nonane-3,1'-cyclobutan]-3'-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-Aminobicyclo[2.2.1]heptane-2,3-diol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-[(1Z)-2,4,4-trimethylcyclopentylidene]acetic acid
  • methyl 3-amino-2-(1H-indol-2-yl)propanoate