2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

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Names

[ CAS No. ]:
277299-70-4

[ Name ]:
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

[Synonym ]:
Eltrombopag II
2-(3,4-Dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
1-(3,4-dimethylphenyl)-3-methyl-3-pyrazolin-5-one
3-methyl-1-(3,4-dimethylphenyl)-2-pyrazolin-5-one
2-(3,4-dimethylphenyl)-5-methyl-4H-pyrazol-3-one
3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-
3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-2,4-dihydro-5-methyl-
Eltrombopag olamine Intermediate 4

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
338.5±52.0 °C at 760 mmHg

[ Melting Point ]:
121.0 to 125.0 °C

[ Molecular Formula ]:
C12H14N2O

[ Molecular Weight ]:
202.252

[ Flash Point ]:
158.5±30.7 °C

[ Exact Mass ]:
202.110611

[ PSA ]:
37.79000

[ LogP ]:
2.64

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.571

Safety Information

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl acetoacetate
  • 3,4-Dimethylphenylhydrazine hydrochloride
  • (3,4-dimethylphenyl)hydrazine

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (4-Chloro-1-naphthalenyl)-1H-indol-3-yl-methanone
  • (S)-Benzyl 1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylate
  • 3,4-Dibromo-2,6-dimethylquinoline
  • 4-(4-(Dimethylamino)butanoyl)-3-(hydroxymethyl)benzonitrile
  • 5-((Pyrrolidin-1-ylsulfonyl)methyl)-1H-indole
  • tert-Butyl (3-(5-amino-6-methoxypyrazin-2-yl)propyl)carbamate
  • (3-(5-(4-Acetamidophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate tert-Butyl Ester
  • tert-Butyl(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate
  • 2-(Benzyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
  • 2-Chloro-N-[4-[(4-methoxyphenyl)methoxy]-2-chloro-6-methylphenyl]acetamide
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