Scutellarin

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Names

[ CAS No. ]:
27740-01-8

[ Name ]:
Scutellarin

[Synonym ]:
5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid
Breviscapin Scutellarein-7-O-β-D-glucuronide
Scutellarein-7β-D-glucuronoside
Scutellarein-7β-D-glucuronide
MFCD01861503
Scutellarein 7-O-β-D-glucuronide
Breviscapin
Scutellarin
7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Breviscapine
Scutellarein 7-b-D-glucuronide
5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid
Scutellarein 7-
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-
Scutellarein-7-O-β-D-glucuronide

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
891.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H18O12

[ Molecular Weight ]:
462.360

[ Flash Point ]:
314.9±27.8 °C

[ Exact Mass ]:
462.079834

[ PSA ]:
207.35000

[ LogP ]:
-0.46

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.764

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • Scutellarein
  • (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

DownStream

  • Scutellarein
  • 4',5,6,7-Tetrahydroxyflavone tetraacetate

Articles

Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia.

J. Neuroinflammation 12 , 11, (2015)

Activated microglial cells release an excess of inflammatory mediators after an ischemic stroke. We reported previously that scutellarin effectively suppressed the inflammatory response induced by act...

[Evaluation on preparation process of brevisapin colon-specific tables and its in vitro release].

Zhongguo Zhong Yao Za Zhi 38(6) , 817-20, (2013)

To prepare the new traditional Chinese medicine preparation--pH-dependent brevisapin colon-specific tablets, and investigate its in vitro release, in order to discuss the feasibility of preparing colo...

Effects of spray-drying and choice of solid carriers on concentrations of Labrasol® and Transcutol® in solid self-microemulsifying drug delivery systems (SMEDDS).

Molecules 18(1) , 545-60, (2013)

Solid self-microemulsifying drug delivery systems (SMEDDS) have been used increasingly for improving the bioavailability of hydrophobic drugs. Labrasol® and Transcutol® are used widely as surfactant a...


More Articles


Related Compounds

  • Scutellarin
  • 6-O-methyl-scutellarin
  • Scutellarin methylester
  • Tetramethyl-O-scutellarin
  • Scutellarin-7-diglucosidic acid