Scutellarin

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Names

[ Name ]:
Scutellarin

[Synonym ]:
5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid
Breviscapin Scutellarein-7-O-β-D-glucuronide
Scutellarein-7β-D-glucuronoside
Scutellarein-7β-D-glucuronide
MFCD01861503
Scutellarein 7-O-β-D-glucuronide
Breviscapin
Scutellarin
7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Breviscapine
Scutellarein 7-b-D-glucuronide
5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid
Scutellarein 7-
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-
Scutellarein-7-O-β-D-glucuronide

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
891.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₈O₁₂

[ Molecular Weight ]:
462.360

[ Flash Point ]:
314.9±27.8 °C

[ Exact Mass ]:
462.079834

[ PSA ]:
207.35000

[ LogP ]:
-0.46

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.764

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Scutellarein
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

DownStream

Scutellarein
4',5,6,7-Tetrahydroxyflavone tetraacetate

Articles

Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia.

J. Neuroinflammation 12 , 11, (2015)

Activated microglial cells release an excess of inflammatory mediators after an ischemic stroke. We reported previously that scutellarin effectively suppressed the inflammatory response induced by act...

[Evaluation on preparation process of brevisapin colon-specific tables and its in vitro release].

Zhongguo Zhong Yao Za Zhi 38(6) , 817-20, (2013)

To prepare the new traditional Chinese medicine preparation--pH-dependent brevisapin colon-specific tablets, and investigate its in vitro release, in order to discuss the feasibility of preparing colo...

Effects of spray-drying and choice of solid carriers on concentrations of Labrasol® and Transcutol® in solid self-microemulsifying drug delivery systems (SMEDDS).

Molecules 18(1) , 545-60, (2013)

Solid self-microemulsifying drug delivery systems (SMEDDS) have been used increasingly for improving the bioavailability of hydrophobic drugs. Labrasol® and Transcutol® are used widely as surfactant a...

Scutellarin
6-O-methyl-scutellarin
Scutellarin methylester
Tetramethyl-O-scutellarin
Scutellarin-7-diglucosidic acid
2-{[(prop-2-en-1-yloxy)carbonyl]amino}-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylic acid
2-[(Dimethylcarbamoyl)sulfanyl]-5-acetamidobenzoic acid
5-(1-{[(Prop-2-en-1-yloxy)carbonyl]amino}cyclobutyl)piperidine-2-carboxylic acid
benzyl N-[1-(pyridin-4-yl)but-3-en-1-yl]carbamate
benzyl N-[3-(but-3-en-1-yl)pyridin-2-yl]carbamate
benzyl N-{[(azetidin-3-yl)methyl](methyl)oxo-lambda6-sulfanylidene}carbamate
4a-(Aminomethyl)-octahydro-1lambda6-thiopyrano[2,3-c]pyrrole-1,1-dione
tert-butyl N-(1-oxo-3,4-dihydro-2H-1lambda6,4-benzothiazin-1-ylidene)carbamate
2-[(1-Acetylpiperidin-4-yl)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid
1-tert-butyl 2-ethyl (2S,4S)-4-fluoropyrrolidine-1,2-dicarboxylate

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