5-Hydroxynicotinic acid

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Names

[ CAS No. ]:
27828-71-3

[ Name ]:
5-Hydroxynicotinic acid

[Synonym ]:
MFCD00129117
1,6-Dihydro-6-oxo-nicotinic acid
6-hydroxypyridine-3-carboxylic acid
5-Hydroxy-nicotinsaeure
3-carboxy-5-hydroxypyridine
6-Hydroxynicotinic acid
6-Hydroxyniacin
T6MVJ EVQ
1,6-dihydro-6-oxopyridine-3-carboxylic acid
3-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-
5-Hydroxynicotinic acid
6-Oxo-1,6-dihydro-3-pyridinecarboxylic acid
1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid
3-Pyridinecarboxylic acid, 5-hydroxy-
Pyridinium, 3-carboxy-5-hydroxy-, inner salt
T6NJ BQ EVQ
5-Hydroxy-3-pyridinecarboxylic acid
5-hydroxypyridinium-3-carboxylate
EINECS 225-682-9
5-Hydroxy-nicotinic acid
3-Pyridinecarboxylic acid,5-hydroxy

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
519.3±35.0 °C at 760 mmHg

[ Melting Point ]:
299 °C

[ Molecular Formula ]:
C6H5NO3

[ Molecular Weight ]:
139.109

[ Flash Point ]:
267.9±25.9 °C

[ Exact Mass ]:
139.026947

[ PSA ]:
70.42000

[ LogP ]:
0.40

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.626

[ Storage condition ]:
Keep Cold

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QT1757500
CHEMICAL NAME :
Nicotinic acid, 5-hydroxy-
CAS REGISTRY NUMBER :
27828-71-3
BEILSTEIN REFERENCE NO. :
0115847
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H5-N-O3
MOLECULAR WEIGHT :
139.12
WISWESSER LINE NOTATION :
T6NJ CQ DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,29,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
QT1757500

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • 5-Bromonicotinic acid
  • 5-Ammonionicotinate
  • Methyl 5-aminonicotinate

DownStream

  • Methyl 5-hydroxynicotinate
  • 5-Hydroxy-6-nitronicotinic acid
  • Ethyl 5-hydroxynicotinate
  • 3-Bromo-5-methoxypyridine
  • 5-Acetoxynicotinic acid
  • Methyl 5-(hydroxymethyl)nicotinate
  • 5-Formyl Nicotinic Acid Methyl Ester

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Unusual mechanism of oxygen atom transfer and product rearrangement in the catalytic reaction of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase.

Biochemistry 36(26) , 8060-70, (1997)

The oxygenation reaction of 2-methyl-3-hydroxypyridine-5-carboxylic acid (MHPC) oxygenase with the substrate, MHPC, was investigated. Two oxygenated flavin intermediates C(4a)-hydroperoxy flavin and C...


More Articles


Related Compounds

  • 5-Hydroxynicotinic acid amide
  • 6-Iodo-5-hydroxynicotinic acid
  • 2-Bromo-5-hydroxynicotinic acid
  • 6-bromo-5-hydroxynicotinic acid
  • 4-CHLORO-5-HYDROXYNICOTINIC ACID
  • 6-Chloro-5-hydroxynicotinic acid
  • 4-Amino-2-methyl-6-(4-pyridinyl)-3(2h)-pyridazinone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (Z)-2-((3-methylthiophen-2-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl benzenesulfonate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine