6-acetylmorphine

Names

[ CAS No. ]:
2784-73-8

[ Name ]:
6-acetylmorphine

[Synonym ]:
[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
470.2ºC at 760mmHg

[ Melting Point ]:
184-189ºC

[ Molecular Formula ]:
C19H21NO4

[ Molecular Weight ]:
327.37400

[ Flash Point ]:
238.2ºC

[ Exact Mass ]:
327.14700

[ PSA ]:
59.00000

[ LogP ]:
1.70680

[ Vapour Pressure ]:
1.83E-09mmHg at 25°C

[ Index of Refraction ]:
1.665

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QC7814500
CHEMICAL NAME :
Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, 6-acetate
CAS REGISTRY NUMBER :
2784-73-8
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312-H319-H331

[ Precautionary Statements ]:
P210-P261-P280-P305 + P351 + P338-P311

[ Hazard Codes ]:
F: Flammable;Xn: Harmful;

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
16-36/37-26

[ RIDADR ]:
UN 1648 3/PG 2

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Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential f...

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Related Compounds

  • 6-Acetylmorphine-d3
  • 6-acetylmorphine-d6
  • 6-Acetylmorphine 3-Glucuronide
  • 6-isothiocyanato-6-pentylundecane
  • 6-Iodo-3-pyridinamine
  • 6,9-Dihydro-7,8-dihydroxy-6,9-dioxo-2-phenazinecarboxylic acid
  • 2-[(6-{[4-(3,4-dichlorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • (3Z)-3-{[(1,3-benzodioxol-5-ylmethyl)amino]methylene}-1-(3-fluorobenzyl)-1H-thieno[3,2-c][1,2]thiazin-4(3H)-one 2,2-dioxide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine