dihydroeugenol

Suppliers

Names

[ Name ]:
dihydroeugenol

[Synonym ]:
p-Propylguaiacol
Coerulignol
Phenol,2-methoxy-4-propyl
Cerulignol
4-n-propylguaiacol
Dihydroeugenol
4-Propylguaiacol
Guaiacylpropane

Chemical & Physical Properties

[ Density]:
1.038

[ Boiling Point ]:
125-126ºC14 mm Hg(lit.)

[ Melting Point ]:
16°C

[ Molecular Formula ]:
C₁₀H₁₄O₂

[ Molecular Weight ]:
166.21700

[ Flash Point ]:
113ºC

[ Exact Mass ]:
166.09900

[ PSA ]:
29.46000

[ LogP ]:
2.35330

[ Vapour Pressure ]:
0.00624mmHg at 25°C

[ Index of Refraction ]:
1.522

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL8050000

CHEMICAL NAME :: Phenol, 2-methoxy-4-propyl-

CAS REGISTRY NUMBER :: 2785-87-7

BEILSTEIN REFERENCE NO. :: 1866292

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H14-O2

MOLECULAR WEIGHT :: 166.24

WISWESSER LINE NOTATION :: QR D3 BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,671,1982 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,671,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,671,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change

REFERENCE :: SIZSAR Sapporo Igaku Zasshi. Sapporo Medical Journal. (Sapporo Igaku Daigaku, Nishi-17-chome, Minami-1-jo, Chuo-ku, Sapporo 060, Japan) V.3- 1952- Volume(issue)/page/year: 3,73,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,671,1982

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H311-H315

[ Precautionary Statements ]:
P280-P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R24;R38

[ Safety Phrases ]:
36/37-45

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
2

[ RTECS ]:
SL8050000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
3302900000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Eugenol
Isoeugenol,mixture of cis and trans
Phenol,2-methoxy-4-(1E)-1-propen-1-yl-
1-(Benzyloxy)-2-methoxy-4-(1-propen-1-yl)benzene
Benzene,2-methoxy-1-(phenylmethoxy)-4-(2-propen-1-yl)-
Triethylsilane
Acetyleugenol
carbon monoxide
Isopropanol

DownStream

coniferyl aldehyde
Methanol
Propylcyclopentane
Propylcyclohexane
Oxalic acid
Vanillin
protocatechuic acid
tarragol
4-Propylcyclohexanol

Customs

[ HS Code ]: 3302900000

Articles

Mosciano, G.

Perfum. Flavor. 27(4) , 68, (2002)

methyldihydroeugenol
6-Amino-dihydroeugenol-methylaether
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
4-Amino-3,6-bis[2-[2,5-dimethoxy-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-5-hydroxy-2,7-naphthalenedisulfonic acid
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1-Chloro-4,5-difluoro-2-(fluoromethoxy)benzene
tert-Butyl-DL-alanine