NH 125

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Names

[ CAS No. ]:
278603-08-0

[ Name ]:
NH 125

[Synonym ]:
1-Benzyl-3-cetyl-2-methylimidazolium iodide
NH125
1H-Imidazolium, 1-hexadecyl-2-methyl-3-(phenylmethyl)-, iodide (1:1)
eEF-2 Kinase Inhibitor,NH125
HMS3229F01
3-Benzyl-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide

Chemical & Physical Properties

[ Melting Point ]:
88.2-94.9ºC

[ Molecular Formula ]:
C27H45IN2

[ Molecular Weight ]:
524.564

[ Exact Mass ]:
524.262756

[ PSA ]:
8.81000

[ LogP ]:
4.61760

[ Appearance of Characters ]:
solid | white to off-white

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: 20 mg/mL

MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.

J. Neurosci. 34(36) , 12230-8, (2014)

The AMP-activated protein kinase (AMPK) is a Ser/Thr kinase that is activated in response to low-energy states to coordinate multiple signaling pathways to maintain cellular energy homeostasis. Dysreg...


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Related Compounds

  • NH-bis(PEG2-propargyl)
  • NH-bis(PEG3-Boc)
  • NH-bis-PEG4
  • NH-(PEG4-acid)2
  • NH[{CH2PO(OEt)2}(CH2COOEt)]
  • NH-bis-PEG2
  • N-(2,6-dimethylphenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • N-(2,4-difluorophenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • 2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-methyl-N-phenylacetamide
  • N-(4-chloro-2-fluorophenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • 6-Chloro-n4-methyl-n4-(2-(pyridin-4-yl)ethyl)pyrimidine-2,4-diamine
  • N-(3-chloro-4-fluorophenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • N-(3,5-dimethoxyphenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • 2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-[3-(methylsulfanyl)phenyl]acetamide
  • 2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(2-ethyl-6-methylphenyl)acetamide
  • (R)-2-(4-Fluorophenyl)morpholine
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