Flumethasone 21-acetate

Suppliers

Names

[ CAS No. ]:
2823-42-9

[ Name ]:
Flumethasone 21-acetate

[Synonym ]:
[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
571.5ºC at 760mmHg

[ Molecular Formula ]:
C24H30F2O6

[ Molecular Weight ]:
452.48800

[ Flash Point ]:
299.4ºC

[ Exact Mass ]:
452.20100

[ PSA ]:
100.90000

[ LogP ]:
2.41450

[ Vapour Pressure ]:
1.93E-15mmHg at 25°C

[ Index of Refraction ]:
1.56

Synthetic Route

Precursor & DownStream

Precursor

  • 9β,11β-epoxy-6α-fluoro-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate
  • SodiuM bicarbonate
  • 6α,9α-Difluor-16α-methyl-11β,17α-dihydroxy-21-acetoxy-3,20-dioxo-Δ4-pregnen
  • 21-acetoxy-6α-fluoro-11β,17-dihydroxy-16α-methyl-pregn-4-ene-3,20-dione
  • Paramethasone Acetate

DownStream


Related Compounds

  • Flumethasone 21-pivalate
  • Icomethasone 21-Acetate
  • Betamethasone 21-Acetate 17-Propionate
  • Budesonide 21-acetate
  • Serratenediol-21-acetate
  • Epi Hydrocortisone 21-Acetate