Rucaparib

Suppliers

Names

[ Name ]:
Rucaparib

[Synonym ]:
6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one,8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]
Kinome_3180
UNII-8237F3U7EH
6H-Azepino[5,4,3-cd]indol-6-one, 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-
AG-014699
Rucaparib
8-fluoro-2-(4-methylaminomethyl-phenyl)-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one
8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]6H-azepino[5,4,3-cd]indol-6-one
8-Fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one
8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
625.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₈FN₃O

[ Molecular Weight ]:
323.364

[ Flash Point ]:
331.9±31.5 °C

[ Exact Mass ]:
323.143402

[ PSA ]:
56.92000

[ LogP ]:
2.85

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.649

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

[4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)-benzyl]-methyl-carbamic acid methyl ester
Rucaparib intermediate
4-(8-Fluoro-3,4,5,6-tetrahydro-6-oxo-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde
WD2000-012547
Methyl 3-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-6-fluoro-1H-indole-4-carboxylate
8-Fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one
2-Bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%