2-Amino-5-chlorophenol

Suppliers

Names

[ Name ]:
2-Amino-5-chlorophenol

[Synonym ]:
5-chloro-ortho-aminophenol
5-chloro-o-aminophenol
2-Amino-5-chlorophenol
4-Chloro-2-hydroxyanilin
5-chloro-2-aminophenol
EINECS 249-020-3
MFCD02093863
4-chloro-2-hydroxylaniline
4-chloro-2-hydroxyaniline
2-hydroxy-4-chloroaniline
Phenol, 2-amino-5-chloro-
2-amino-5-chloro-phenol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
267.7±25.0 °C at 760 mmHg

[ Melting Point ]:
145-153 °C(lit.)

[ Molecular Formula ]:
C₆H₆ClNO

[ Molecular Weight ]:
143.571

[ Flash Point ]:
115.7±23.2 °C

[ Exact Mass ]:
143.013794

[ PSA ]:
46.25000

[ LogP ]:
1.58

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.651

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-(4-chloro-2-hydroxyphenyl)-2,6-difluorobenzamide
5-Chloro-2-nitrophenol
4-Chloroaniline
2-Ketoglutaric acid
1-chloro-4-nitrosobenzene
Sodium 2-oxopentanedioate hydrate (2:1:2)
4-Chloronitrobenzene
Acetamide,N-(4-chloro-2-hydroxyphenyl)-
acetic acid-(4-amino-2-hydroxy-anilide)
O-(3-chlorophenyl)hydroxylamine

DownStream

5-chloro-2-phenyl-1,3-benzoxazole
2,6-Dichlorobenzoxazole
N-(4-Chloro-2-ethoxyphenyl)-2,2-dimethylpropanamide
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
2,5-Dichlorophenol
2-Amino-6-chlorobenzoxazole
N-(6-chloro-benzoxazol-2-yl)-N'-isopropyl-guanidine
5-Chloro-2-iodophenol
2-amino-7-chlorophenoxazin-3-one
Acetamide,N-(4-chloro-2-hydroxyphenyl)-

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Chemoselective nitro group reduction and reductive dechlorination initiate degradation of 2-chloro-5-nitrophenol by Ralstonia eutropha JMP134.

Appl. Environ. Microbiol. 65(6) , 2317-23, (1999)

Ralstonia eutropha JMP134 utilizes 2-chloro-5-nitrophenol as a sole source of nitrogen, carbon, and energy. The initial steps for degradation of 2-chloro-5-nitrophenol are analogous to those of 3-nitr...

Nephrotoxic potential of 2-amino-5-chlorophenol and 4-amino-3-chlorophenol in Fischer 344 rats: comparisons with 2- and 4-chloroaniline and 2- and 4-aminophenol.

Toxicology 108(1-2) , 109-23, (1996)

Nephrotoxicity occurs following intraperitoneal (i.p.) administration of 2-chloroaniline or 4-chloroaniline hydrochloride to Fischer 344 rats, but the nephrotoxicant chemical species and mechanism of ...

Novel partial reductive pathway for 4-chloronitrobenzene and nitrobenzene degradation in Comamonas sp. strain CNB-1.

Appl. Environ. Microbiol. 72(3) , 1759-65, (2006)

Comamonas sp. strain CNB-1 grows on 4-chloronitrobenzene (4-CNB) and nitrobenzene as sole carbon and nitrogen sources. In this study, two genetic segments, cnbB-orf2-cnbA and cnbR-orf1-cnbCaCbDEFGHI, ...