5,6-dimethyl-2-Thiouracil

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Names

[ CAS No. ]:
28456-54-4

[ Name ]:
5,6-dimethyl-2-Thiouracil

[Synonym ]:
5,6-dimethyl-2-sulfanylidene-1H-pyrimidin-4-one
MFCD00278872

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
347.3ºC at 760mmHg

[ Melting Point ]:
284-288ºC(lit.)

[ Molecular Formula ]:
C6H8N2OS

[ Molecular Weight ]:
156.20600

[ Flash Point ]:
163.9ºC

[ Exact Mass ]:
156.03600

[ PSA ]:
84.81000

[ LogP ]:
1.08770

[ Vapour Pressure ]:
2.7E-05mmHg at 25°C

[ Index of Refraction ]:
1.61

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9887000
CHEMICAL NAME :
Uracil, 5,6-dimethyl-2-thio-
CAS REGISTRY NUMBER :
28456-54-4
BEILSTEIN REFERENCE NO. :
0118811
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H8-N2-O-S
MOLECULAR WEIGHT :
156.22
WISWESSER LINE NOTATION :
T6MYMVJ BUS E1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - antipsychotic
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 6,490,1958

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YQ9887000

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl 2-methylacetoacetate
  • methyl 2-methyl-3-oxobutanoate

DownStream

  • 4-Chloro-5,6-dimethylpyrimidine
  • 2,4(1H,3H)-Pyrimidinedione,3,5,6-trimethyl-
  • 5,6-DIMETHYLPYRIMIDIN-4-OL
  • 2,4-Dihydroxy-5,6-dimethylpyrimidine
  • 2,4-Dichloro-5,6-dimethylpyrimidine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5,6-dimethyl-2-(3-methylphenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione
  • 5,6-dimethyl-2-methylsulfanyl-3H-thieno[2,3-d]pyrimidin-4-one
  • 5,6-dimethyl-2,7-dihydrocyclopenta[c]pyridin-1-one
  • 5,6-dimethyl-2-(5-methyl-1,2-dihydropyrazol-3-ylidene)benzimidazole
  • 5,6-dimethyl-2-(trifluoromethyl)-1H-benzimidazole
  • 5,6-Dimethyl-2-piperidin-4-yl-1H-benzimidazole