4-Amino-1H-pyrazole

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Names

[ CAS No. ]:
28466-26-4

[ Name ]:
4-Amino-1H-pyrazole

[Synonym ]:
1H-pyrazole-4-amine
3-pyrazolylamine
4-NH2-pyrazole
1H-Pyrazol-4-amine
4-Amino-1H-pyrazole
Pyrazole,4-amino
1H-Pyrazol-5-amine
4-Aminopyrazole
1H-PYRAZOL-4-YLAMINE
1H-pyrazol-3-amine
pyrazole-4-ylamine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
334.5±15.0 °C at 760 mmHg

[ Melting Point ]:
75-77ºC

[ Molecular Formula ]:
C3H5N3

[ Molecular Weight ]:
83.092

[ Flash Point ]:
182.6±7.6 °C

[ Exact Mass ]:
83.048347

[ PSA ]:
54.70000

[ LogP ]:
-1.10

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.648

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ4993000
CHEMICAL NAME :
Pyrazole, 4-amino-
CAS REGISTRY NUMBER :
28466-26-4
BEILSTEIN REFERENCE NO. :
0001619
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H5-N3
MOLECULAR WEIGHT :
83.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,592,1970

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UQ4993000

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Nitro-1H-pyrazole
  • 1H-Pyrazole-3-carboxylicacid,4-amino-
  • Hydrochloric acid
  • pyrazolo[4,3-d]pyrimidine-5,7-(1H,4H,6H)-dione
  • acetic acid

DownStream

  • 4-Iodopyrazole
  • 1H-Pyrazole,5-chloro-1-ethyl-4-nitro-
  • 2,4-DICHLORO-6-METHYLNICOTINALDEHYDE

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • 4-Amino-1H-pyrazole-5-carboxamide
  • 4-Amino-1H-pyrazole-3-carbonitrile
  • 4-Amino-1H-pyrazole-5-carbohydrazide
  • 4-amino-1H-pyrazole-5-carboxylic acid
  • 5-Chloro-3-Methyl-4-amino-1H-pyrazole
  • Ethyl4-amino-1H-pyrazole-5-carboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • tert-Butyl 3-amino-2-(2-methoxyphenyl)pyrrolidine-1-carboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide