2-hydroxy-5-methoxybenzamide

Names

[ CAS No. ]:
28534-37-4

[ Name ]:
2-hydroxy-5-methoxybenzamide

[Synonym ]:
5-Methoxysalicylamid
Benzamide,2-hydroxy-5-methoxy
2-hydroxy-5-methoxy-benzamide
5-methoxysalicylamide
Salicylamide,5-methoxy
2-Hydroxy-5-methoxy-benzoesaeure-amid

Chemical & Physical Properties

[ Density]:
1.28 g/cm3

[ Boiling Point ]:
320.5ºC at 760 mmHg

[ Molecular Formula ]:
C8H9NO3

[ Molecular Weight ]:
167.16200

[ Flash Point ]:
147.7ºC

[ Exact Mass ]:
167.05800

[ PSA ]:
72.55000

[ LogP ]:
1.20000

[ Vapour Pressure ]:
0.000168mmHg at 25°C

[ Index of Refraction ]:
1.584

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN7790000
CHEMICAL NAME :
Salicylamide, 5-methoxy-
CAS REGISTRY NUMBER :
28534-37-4
BEILSTEIN REFERENCE NO. :
2719228
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H9-N-O3
MOLECULAR WEIGHT :
167.18
WISWESSER LINE NOTATION :
ZVR BQ EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 2-hydroxy-5-methoxybenzoate
  • Mequinol
  • Trichloroacetonitrile

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 2-Hydroxy-5-methoxybenzamide
  • N,N-diethyl-2-hydroxy-5-methoxybenzamide
  • N-(2-chlorophenyl)-2-hydroxy-5-methoxybenzamide
  • N-[(4-chlorophenyl)methyl]-2-hydroxy-5-methoxybenzamide
  • N-(4-amino-1-methyl-2,6-dioxo-3-phenylpyrimidin-5-yl)-2-hydroxy-5-methoxybenzamide
  • N-[6-amino-1-(4-fluorophenyl)-3-methyl-2,4-dioxopyrimidin-5-yl]-2-hydroxy-5-methoxybenzamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • [1-(2-Bromophenyl)ethyl](methyl)amine
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide