4-Benzyl-2-hydroxy-3-morpholinone

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Names

[ CAS No. ]:
287930-73-8

[ Name ]:
4-Benzyl-2-hydroxy-3-morpholinone

[Synonym ]:
4-Benzyl-2-hydroxy-3-morpholinone
4-Benzyl-2-hydroxy-morpholin-3-one
3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-
benzyl lactam lactol
4-Benzyl-2-hydroxymorpholin-3-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
441.7±45.0 °C at 760 mmHg

[ Melting Point ]:
136 °C

[ Molecular Formula ]:
C11H13NO3

[ Molecular Weight ]:
207.226

[ Flash Point ]:
220.9±28.7 °C

[ Exact Mass ]:
207.089539

[ PSA ]:
49.77000

[ LogP ]:
0.27

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.595

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Benzyl-2,3-Morpholinedione
  • Glyoxylic acid
  • 2-(Benzylamino)ethanol
  • 2-Oxoacetic acid
  • methyl 2-(hydroxymethoxy)acetate
  • methyl 2-methoxy-2-((2-methoxypropan-2-yl)oxy)acetate

DownStream

  • (2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • (2R)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]morpholin-3-one
  • Aprepitant

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-benzyloxy-2-hydroxy-3,6-dimethoxybenzaldehyde
  • 4-benzyl-2-hydroxy-2-methylmorpholin-3-one
  • 4-benzyl-2-hydroxy-isoquinoline-1,3(2H,4H)-dione
  • 4-benzyl-2-[[5-benzyl-2-hydroxy-3-(hydroxymethyl)phenyl]disulfanyl]-6-(hydroxymethyl)phenol
  • 4-benzyl-2-(hydroxymethyl)-6-sulfanylphenol
  • 4-(2-hydroxy-3-tert-butylaminopropoxy)-2-methylindole
  • Benzonitrile, 4-amino-2-[(1R,2S)-1-amino-2-hydroxypropyl]-
  • 3-((3-Iodo-4-methylphenyl)amino)propanoic acid
  • Pralidoxime iodide, (Z)-
  • 2-Chloro-6-[methyl(prop-2-yn-1-yl)amino]pyrimidine-4-carboxylic acid
  • (E)-2-(1-methyl-1H-benzo[d]imidazol-2(3H)-ylidene)-3-oxo-3-(4-(pyrrolidin-1-ylsulfonyl)phenyl)propanenitrile
  • 6-Methyl-2-phenethylsulfanyl-1H-pyrimidin-4-one
  • 1-(5-Iodo-2-methylphenyl)guanidine
  • N-Butyl-3-fluoro-2-iodoaniline
  • 6-Bromo-2-phenylthieno[3,2-d]pyrimidin-4(3h)-one
  • (3,4-dihydro-2H-1-benzopyran-3-yl)hydrazine
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