(1S)-1-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-[2-(2-hyd roxy-2-propanyl)phenyl]-1-propanol

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Names

[ CAS No. ]:
287930-77-2

[ Name ]:
(1S)-1-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-[2-(2-hyd roxy-2-propanyl)phenyl]-1-propanol

Chemical & Physical Properties

[ Molecular Formula ]:
C29H28ClNO2

[ Molecular Weight ]:
457.99100

[ Exact Mass ]:
457.18100

[ PSA ]:
53.35000

[ LogP ]:
6.95220

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 2-[(3S)-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoate
  • Methylmagnesium chloride
  • 7-CHLORO-2-VINYLQUINOLINE
  • (3S)-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-4,5-dihydro-3H-benzo[c]oxepin-1-one
  • (+/-)-methyl 2-(3-(3-bromophenyl)-3-hydroxypropyl)benzoate
  • (+/-)-1-(3-bromophenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-propanol
  • 1-(3-bromophenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-one
  • Methyl (E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate

DownStream

  • L 768232
  • Montelukast Dicyclohexylamine Salt
  • Montelukast
  • Montelukast sodium
  • Montelukast Bis-sulfide
  • 1-[[[(1R)-1-[3-[(1S)-1-[[[1-(Carboxymethyl)cyclopropyl]methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid

Related Compounds

  • {5-[(Fluorosulfonyl)oxy]-2-methyl-3-[2-(trimethylsilyl)ethynyl]phenyl}methanesulfonyl fluoride
  • 2-Methyl-3-[(piperazin-1-yl)methyl]-5-[2-(trimethylsilyl)ethynyl]phenyl sulfurofluoridate
  • 4-Methyl-3-[(piperazin-1-yl)methyl]-5-[2-(trimethylsilyl)ethynyl]phenyl sulfurofluoridate
  • Tert-butyl 3-[(fluorosulfonyl)oxy]-4-methyl-5-[2-(trimethylsilyl)ethynyl]benzoate
  • (2RS,3RS)-1-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoyl]-2-methylpiperidine-3-carboxylic acid
  • Tert-butyl 3-[(fluorosulfonyl)oxy]-2-methyl-5-[2-(trimethylsilyl)ethynyl]benzoate
  • Tert-butyl 4-{3-amino-5-[(fluorosulfonyl)methyl]-2-methylphenyl}piperazine-1-carboxylate
  • Tert-butyl 4-{5-amino-3-[(fluorosulfonyl)methyl]-2-methylphenyl}piperazine-1-carboxylate
  • Tert-butyl 4-{[3-amino-5-(fluorosulfonyl)-4-methylphenyl]methyl}piperazine-1-carboxylate
  • tert-butyl N-[3-(fluorosulfonyl)-2-methyl-5-[(piperazin-1-yl)methyl]phenyl]carbamate
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