Thiazole

Names

[ CAS No. ]:
288-47-1

[ Name ]:
Thiazole

[Synonym ]:
FEMA 3615
THIAN-4-ONEOXIME
thiazol
MFCD00005315
Thiazole
FEMA NUMBER 3615
EINECS 206-021-3
1,3-Thiazole

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
116.5±9.0 °C at 760 mmHg

[ Melting Point ]:
-33°C

[ Molecular Formula ]:
C₃H₃NS

[ Molecular Weight ]:
85.128

[ Flash Point ]:
22.2±0.0 °C

[ Exact Mass ]:
84.998619

[ PSA ]:
41.13000

[ LogP ]:
0.44

[ Vapour Pressure ]:
21.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.543

[ Storage condition ]:
Flammables area

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
slightly soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ1290000

CHEMICAL NAME :: Thiazole

CAS REGISTRY NUMBER :: 288-47-1

BEILSTEIN REFERENCE NO. :: 0103852

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H3-N-S

MOLECULAR WEIGHT :: 85.13

WISWESSER LINE NOTATION :: T5N CSJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 983 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 4 umol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 321,213,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83284 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 212 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83284 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1849 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R10;R22

[ Safety Phrases ]:
S16-S26-S39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XJ1290000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,5-Dibromothiazole
4-Bromothiazole
2-(Trimethylsilyl)thiazole
1-Boc-2-piperidinecarbaldehyde
2-Thienylthiol
2-bromoethyl isothiocyanate
2,6-lutidine
Ethyl bromopyruvate
2-Methylmercaptobenzothiazole
2-Bromobutyric acid

DownStream

N-Phenacylthiazolium bromide
1,3-Thiazol-2-ylboronic acid
2-Bromo-1-thiazol-2-yl-ethanone
THIAZOLE N-OXIDE
2-(Methylsulfanyl)-1,3-thiazole
2-Bromothiazole
2,5-Dibromothiazole
3-pyridin-2-yltriazolo[1,5-a]pyridine

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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