nordoxepin

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Names

[ CAS No. ]:
2887-91-4

[ Name ]:
nordoxepin

[Synonym ]:
(3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methylpropan-1-amine
3-Dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-1-propanamine
1-Propanamine,3-dibenzb,eoxepin-11(6H)-ylidene-N-methyl-,hydrochloride
11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE
nordoxepin
N-DesMethyldoxepin-d3 Hydrochloride
1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-, (3Z)-
11(6h)-(3-[methylamino]propylidene)dibenz[b,e]oxepine
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-
NorDoxepinHydrochloride
(3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methyl-1-propanamine
3-Dibenzo[b,e]oxepin-11(6H)-ylidene-N-methylpropan-1-amine
demethyldoxepin
3-(Dibenz[b,e]oxepin-11(6H)-ylidene)-N-Methyl
N-Desmethyldoxepin
N-DesMethyldoxepin Hydrochloride

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
420.8±44.0 °C at 760 mmHg

[ Melting Point ]:
159-160ºC

[ Molecular Formula ]:
C18H20ClNO

[ Molecular Weight ]:
265.350

[ Flash Point ]:
174.5±17.9 °C

[ Exact Mass ]:
265.146667

[ PSA ]:
21.26000

[ LogP ]:
4.59

[ Appearance of Characters ]:
powder | white to off-white

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.635

[ Storage condition ]:
-20°C Freezer

MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
22-50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
3

Articles

Determination of perhexiline and its metabolite hydroxyperhexiline in human plasma by liquid chromatography/tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(27) , 3025-30, (2009)

Perhexiline is a drug that is used for treatment of moderate to severe angina pectoris that has not responded to other treatment. It has a low therapeutic index, and saturable metabolism that is also ...

Simultaneous determination of doxepin and nordoxepin in serum using high-performance liquid chromatography.

J. Chromatogr. A. 419 , 445-51, (1987)

Quantitative determination of E- and Z-doxepin and E- and Z-desmethyldoxepin by high-performance liquid chromatography.

Ther. Drug Monit. 17(4) , 371-6, (1995)

A high-performance liquid chromatographic (HPLC) method was developed for the quantitative, simultaneous determination of the following four compounds in serum: E-doxepin, Z-doxepin, E-desmethyldoxepi...


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Related Compounds

  • Nordoxepin
  • Nordoxepin D3 hydrochloride