Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

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Names

[ CAS No. ]:
289042-11-1

[ Name ]:
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

[Synonym ]:
MFCD08235142
Z-6
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-carboxylate
Rosuvastatin intermediate R-1-1
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinecarboxylate
5-Pyrimidinecarboxylic acid, 4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, methyl ester
ZD-1
methyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidine-5-carboxylate
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
552.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H20FN3O4S

[ Molecular Weight ]:
381.422

[ Flash Point ]:
287.6±32.9 °C

[ Exact Mass ]:
381.115845

[ PSA ]:
97.84000

[ LogP ]:
1.59

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.557

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
  • sodium salt of N-methyl-N-methylsulfonylamine
  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(METHYLAMINO)PYRIMIDINE-5-CARBOXYLATE
  • Methanesulfonyl chloride
  • N-Methylmethane sulfonamide
  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHANESULFONAMIDO)]PYRIMIDINE-5-CARBOXYLATE
  • Sodium tert-pentoxide

DownStream

  • Methanesulfonamide,N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl
  • 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-methanol

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • 5-(6-Methyl-5-nitro-pyridin-3-ylethynyl)-pyrimidin-2-ylamine
  • 5-[(3-aminophenyl)ethynyl]-N-(3-morpholin-4-ylpropyl)pyrimidin-2-amine
  • 4-(4-aminophenyl)-3-methyl-1H-1,2,4-triazol-5-one
  • 4-(3-aminophenyl)-3-methyl-1H-1,2,4-triazol-5-one
  • 1-(3-Aminophenyl)-4-isopropylpiperazin-2-one
  • 5-[2-[3-[2-(4-Hydroxypiperidin-1-yl)ethyl]anilino]pyrimidin-4-yl]thiophene-2-carboxylic acid
  • 2-Fluoro-6-(2-methoxyethoxy)benzoic acid
  • 2,2,2-Trifluoroethyl 4-methylpiperidine-1-carboxylate
  • 3-Methyl-1-[(1-methylethyl)thio]-2-butanone
  • 1H-Benzimidazole, 2-(1-methylethyl)-6-(trifluoromethyl)-
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