Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

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Names

[ CAS No. ]:
289042-11-1

[ Name ]:
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

[Synonym ]:
MFCD08235142
Z-6
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-carboxylate
Rosuvastatin intermediate R-1-1
Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinecarboxylate
5-Pyrimidinecarboxylic acid, 4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-, methyl ester
ZD-1
methyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidine-5-carboxylate
Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
552.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H20FN3O4S

[ Molecular Weight ]:
381.422

[ Flash Point ]:
287.6±32.9 °C

[ Exact Mass ]:
381.115845

[ PSA ]:
97.84000

[ LogP ]:
1.59

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.557

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
  • sodium salt of N-methyl-N-methylsulfonylamine
  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(METHYLAMINO)PYRIMIDINE-5-CARBOXYLATE
  • Methanesulfonyl chloride
  • N-Methylmethane sulfonamide
  • METHYL 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHANESULFONAMIDO)]PYRIMIDINE-5-CARBOXYLATE
  • Sodium tert-pentoxide

DownStream

  • Methanesulfonamide,N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl
  • 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-methanol

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • 6-Amino-3-fluoro-2-hydroxypyridine
  • Tert-butyl 3-(aminomethyl)-2-methylazetidine-1-carboxylate
  • 3-Amino-4-fluoropicolinaldehyde
  • (3S)-3-Amino-3-(3-fluoro-4-methoxyphenyl)propanenitrile
  • (1R)-1-(4-Bromo-3-methylphenyl)prop-2-enylamine
  • 5-((1R,2R)-1-Amino-2-hydroxypropyl)-2-chlorophenol
  • 2-Methyl-1,1-dioxo-1lambda6-thiolane-3-sulfonamide
  • (3R)-3-Amino-3-(2-methyl-2H-1,2,3-triazol-4-yl)propanoic acid
  • (2R)-2-amino-2-(2,4-difluoro-6-methoxyphenyl)ethan-1-ol
  • (S)-7-Bromo-8-fluorochroman-4-amine
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