TRAM-34

Suppliers

Names

[ Name ]:
TRAM-34

[Synonym ]:
TRAM-34
1H-Pyrazole, 1-[(2-chlorophenyl)diphenylmethyl]-
1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-pyrazole
1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole
Clotrimazole Impurity 8

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
510.2±50.0 °C at 760 mmHg

[ Melting Point ]:
145-147ºC

[ Molecular Formula ]:
C₂₂H₁₇ClN₂

[ Molecular Weight ]:
344.837

[ Flash Point ]:
262.4±30.1 °C

[ Exact Mass ]:
344.108032

[ PSA ]:
17.82000

[ LogP ]:
5.65

[ Appearance of Characters ]:
solid | off-white

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.617

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: ~11 mg/mL | Soluble in DMSO at 2mg/ml. Insoluble in water

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H413

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933199090

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Kv1.3 lymphocyte potassium channel inhibition as a potential novel therapeutic target in acute ischemic stroke.

CNS Neurol. Disord. Drug Targets 13(5) , 801-6, (2014)

Stroke-induced immunosuppression (SIIS) leads to severe complications in stroke patients, including an increased risk of infections. However, functional alterations of T lymphocytes during SIIS are po...

Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channels.

Br. J. Pharmacol. 172 , 3484-94, (2015)

Eugenol, a vanilloid molecule found in some dietary plants, relaxes vasculature in part via an endothelium-dependent process; however, the mechanisms involved are unclear. Here, we investigated the en...

Impairment of IKCa channels contributes to uteroplacental endothelial dysfunction in rat diabetic pregnancy.

Am. J. Physiol. Heart Circ. Physiol. 309 , H592-604, (2015)

Diabetes in rat pregnancy is associated with impaired vasodilation of the maternal uteroplacental vasculature. In the present study, we explored the role of endothelial cell (EC) Ca(2+)-activated K(+)...