2-Chlorobenzenesulfonyl chloride

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Names

[ CAS No. ]:
2905-23-9

[ Name ]:
2-Chlorobenzenesulfonyl chloride

[Synonym ]:
EINECS 220-807-3
Benzenesulfonyl chloride, 2-chloro-
Benzenesulfonyl chloride, o-chloro- (6CI,7CI,8CI)
2-chlorobenzene-1-sulfonyl chloride
o-Chlorobenzenesulfochloride
MFCD00051520
2-chloro-benzenesulfonyl chloride
2-Chlorobenzenesulphonyl chloride
WSGR BG
2-Chlorobenzenesulfonyl chloride
o-chlorobenzene sulfonic acid chloride
Benzenesulfonyl chloride,2-chloro
2-chlorophenylsulfonyl chloride
ortho-chlorobenzenesulfonyl chloride
o-Chlorobenzenesulfonyl chloride

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
290.8±23.0 °C at 760 mmHg

[ Melting Point ]:
28ºC

[ Molecular Formula ]:
C6H4Cl2O2S

[ Molecular Weight ]:
211.066

[ Flash Point ]:
129.7±22.6 °C

[ Exact Mass ]:
209.930908

[ PSA ]:
42.52000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB8925500
CHEMICAL NAME :
Benzenesulfonyl chloride, 2-chloro-
CAS REGISTRY NUMBER :
2905-23-9
BEILSTEIN REFERENCE NO. :
0974321
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H4-Cl2-O2-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 54(4),72,1989
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 54(4),72,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7732 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 54(4),72,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2750 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 54(4),72,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
7320 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 54(4),72,1989

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2920 8/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
DB8925500

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Chlorophenylboronic aicd
  • 2-Chloroaniline
  • 2-chlorobenzenediazonium

DownStream

  • 1-(2-chlorophenyl)sulfonyl-5-ethoxypyrrolidin-2-one
  • bis(2-chlorophenyl) disulfide
  • chlorophenyl isocyanate
  • 2-chlorobenzenesulfonic acid
  • 2-Chlorobezenesulfonamide
  • SODIUM 2-CHLOROBENZENESULFINATE
  • N-Methylaniline
  • 2-Chlorothiophenol
  • 2-Chloro-N-methylbenzenesulfonamide
  • 1-(2-chlorophenyl)sulfonyl-3-(4,6-dimethylpyrimidin-2-yl)urea

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

[Experimental research on the toxicity of the product orthochlorobenzene sulfur chloride].

Rev. Med. Chir. Soc. Med. Nat. Iasi. 97(2) , 281-6, (1993)

The potential of toxic action in rats of orthochlorbenzol sulphochloride, administered intragastrically in single doses and in daily doses included in food, was estimated. Other bioenzymatic parameter...

[Toxicologic and hygienic characteristics of O-chlorobenzenesulfochloride].

Gig. Sanit. (4) , 72-3, (1989)


More Articles


Related Compounds

  • 4-Bromo-2-chlorobenzenesulfonyl chloride
  • 5-Bromo-2-chlorobenzenesulfonyl chloride
  • 5-nitro-2-chlorobenzenesulfonyl chloride
  • 5-Acetyl-2-chlorobenzenesulfonyl chloride
  • 4-acetamido-2-chlorobenzenesulfonyl chloride
  • 5-Methanesulfonyl-2-chlorobenzenesulfonyl chloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-Amino-5-methyl-1H-indazole-7-carboxylic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • tert-butyl (7S,8aR)-7-hydroxy-octahydropyrrolo[1,2-a]piperazine-2-carboxylate
  • N-((4,6-dimethoxy-1,3,5-triazin-2-yl)methyl)-2-((4-fluorophenyl)thio)acetamide
  • ((10-Ethyl-10H-phenothiazin-3-yl)methyl)triphenylphosphonium iodide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide