3-(carbamoylamino)-2-methyl-propanoic acid

Names

[ Name ]:
3-(carbamoylamino)-2-methyl-propanoic acid

[Synonym ]:
3-carbamoylamino-2-methylpropanoic acid
3-Ureido-isobuttersaeure
3-ureido-2-methyl-propanoic acid
3-Ureidoisobutyrate
3-(carbamoylamino)-2-methylpropanoic acid
DL-3-Ureidoisobutyric acid

Chemical & Physical Properties

[ Density]:
1.263g/cm3

[ Boiling Point ]:
317.5ºC at 760mmHg

[ Molecular Formula ]:
C₅H₁₀N₂O₃

[ Molecular Weight ]:
146.14400

[ Flash Point ]:
145.8ºC

[ Exact Mass ]:
146.06900

[ PSA ]:
93.41000

[ LogP ]:
0.28010

[ Vapour Pressure ]:
8.12E-05mmHg at 25°C

[ Index of Refraction ]:
1.497

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities.

Hum. Mol. Genet. 13(22) , 2793-801, (2004)

beta-Ureidopropionase deficiency is an inborn error of the pyrimidine degradation pathway, affecting the cleavage of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyric acid. In this study, we...

Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 791(1-2) , 371-80, (2003)

Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil. To assess whether urinary levels of pyrimidines and their m...

Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine.

J. Mass Spectrom. 37(9) , 954-62, (2002)

Dihydropyrimidine dehydrogenase (DHPDase), dihydropyrimidinase (DHPase) and beta-ureidopropionase (betaUPase) are the enzymes that catalyze the first, second, and third steps of the degradation of pyr...

Propanoic acid,3-[(aminocarbonyl)amino]-2-methyl-3-oxo-, methyl ester
3-(benzylamino)-2-methyl-propanoic acid
3-Diisobutoxyphosphinothioylsulfanyl-2-Methyl-Propanoic Acid
3-(carbamoylamino)-2-hydroxy-2-methyl-3-oxopropanoic acid
3-(2-methoxyphenyl)-2-methyl-propanoic acid
3-[2-Methyl-4-(trifluoromethoxy)phenyl]propanoic acid