1H-Indole-3-acetamide,N,N-dimethyl-α-oxo-

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Names

[ CAS No. ]:
29095-44-1

[ Name ]:
1H-Indole-3-acetamide,N,N-dimethyl-α-oxo-

[Synonym ]:
indol-3-yl-glyoxylic acid dimethylamide
3-indole-N',N'-dimethylglyoxamide
N,N-dimethyl-3-indoleglyoxylamide
3-INDOLYLGLYOXYLDIMETHYLAMIDE
N,N-dimethylindole-3-glyoxylamide
n,n-dimethyl-indole-3-glyoxylamid
Oxalylindol-3-N,N-dimethylglyoxylamid
Indol-3-yl-glyoxylsaeure-dimethylamid

Chemical & Physical Properties

[ Density]:
1.266 g/cm3

[ Boiling Point ]:
399.6ºC at 760 mmHg

[ Molecular Formula ]:
C12H12N2O2

[ Molecular Weight ]:
216.23600

[ Flash Point ]:
195.5ºC

[ Exact Mass ]:
216.09000

[ PSA ]:
53.17000

[ LogP ]:
1.43880

[ Vapour Pressure ]:
3.38E-08mmHg at 25°C

[ Index of Refraction ]:
1.704

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL8792260
CHEMICAL NAME :
Indole-3-glyoxylamide, N,N-dimethyl-
CAS REGISTRY NUMBER :
29095-44-1
BEILSTEIN REFERENCE NO. :
0179523
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H12-N2-O2
MOLECULAR WEIGHT :
216.26
WISWESSER LINE NOTATION :
T56 BNJ DVVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity)
REFERENCE :
FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

Safety Information

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Indole
  • Oxalyl chloride
  • Dimethylamine
  • indole-3-glyoxylyl chloride
  • Dimethylamine hydrochloride
  • Methyl indolyl-3-glyoxylate
  • N,N-Dimethylformamide
  • 2-(1H-IMIDAZOL-1-YL)ACETAMIDE

DownStream

  • Dimethyltryptamine
  • 2-(5-chloro-1H-indol-3-yl)-N,N-dimethylethanamine
  • 2-(1-butylindol-3-yl)-N,N-dimethyl-2-oxoacetamide
  • U 5092
  • 2-dimethylamino-1-(1-ethylindol-3-yl)ethanol
  • N,N-dimethyl-2-(1-methylindol-3-yl)-2-oxo-acetamide

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 5-bromo-N,N-dimethyl-α-oxo-1H-indole-3-acetamide
  • 1H-Indole-3-acetamide,N,N,2-trimethyl-a-oxo-
  • 3-(2-(diethylamino)-2-oxoacetyl)-1H-indol-4-yl acetate
  • 2-(1,2-dimethylindol-3-yl)-N,N-diethyl-2-oxo-acetamide
  • WAY-270250
  • WAY-270252