Toloxatone
Suppliers
Names
[ CAS No. ]:
29218-27-7
[ Name ]:
Toloxatone
[Synonym ]:
5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone Humoryl
Toloxatone
5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one
5-hydroxymethyl-3-(3-methylphenyl)-2-oxazolidinone
ToloxatonetoloxatonetoloxatoneToloxatone
Perenum
EINECS 249-522-2
MFCD00865391
Humoryl
5-(hydroxymethyl)-3-m-tolyl-2-oxazolidinone
5-Hydroxymethyl-3-(3-methylphenyl)oxazolidin-2-one
Chemical & Physical Properties
[ Density]:
1.245g/cm3
[ Boiling Point ]:
358.9ºC at 760mmHg
[ Melting Point ]:
76°
[ Molecular Formula ]:
C11H13NO3
[ Molecular Weight ]:
207.23
[ Flash Point ]:
170.9ºC
[ Exact Mass ]:
207.09000
[ PSA ]:
49.77000
[ LogP ]:
1.37750
[ Vapour Pressure ]:
8.9E-06mmHg at 25°C
[ Index of Refraction ]:
1.57
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
DMSO: >10mg/mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RQ2867500
- CHEMICAL NAME :
- 2-Oxazolidinone, 5-hydroxymethyl-3-(m-tolyl)-
- CAS REGISTRY NUMBER :
- 29218-27-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H13-N-O3
- MOLECULAR WEIGHT :
- 207.25
- WISWESSER LINE NOTATION :
- T5NVOTJ AR C1& D1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1225 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - coma Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 1,569,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - coma Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 1,569,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - coma Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 1,569,1976
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ RIDADR ]:
UN 3249
[ RTECS ]:
RQ2867500
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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