2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetonitrile

Names

[ CAS No. ]:
29277-73-4

[ Name ]:
2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetonitrile

[Synonym ]:
{4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl}acetonitrile
(4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl)acetonitrile
Benzeneacetonitrile, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
Atenolol Impurity 8

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
448.5±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H20N2O2

[ Molecular Weight ]:
248.321

[ Flash Point ]:
225.1±27.3 °C

[ Exact Mass ]:
248.152481

[ PSA ]:
65.28000

[ LogP ]:
1.10

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.528

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(2-Oxiranylmethoxy)benzeneacetonitrile
  • isopropylamine
  • 4-Hydroxybenzyl alcohol
  • 4-Hydroxyphenylacetonitrile
  • N-(oxiran-2-ylmethyl)propan-2-amine

DownStream

  • Atenolol
  • ethyl 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetate