1,3-Benzenedicarboxaldehyde,4-hydroxy-5-methoxy-

Suppliers

Names

[ CAS No. ]:
2931-90-0

[ Name ]:
1,3-Benzenedicarboxaldehyde,4-hydroxy-5-methoxy-

[Synonym ]:
4-Hydroxy-5-methoxy-isophthalaldehyd
4-Hydroxy-5-methoxyisophthalic dialdehyde
5-formyl-3-methoxysalicylaldehyde
5-Formyl-vanilin
4-Hydroxy-5-methoxyisophthalaldehyde
5-formyl-2-hydroxy-3-methoxybenzaldehyde
2-methoxy-4,6-diformylphenol
5-formylvanillin
EINECS 220-901-4
ISOPHTHALDEHYDE,4-HYDROXY-5-METHOXY

Chemical & Physical Properties

[ Density]:
1.332g/cm3

[ Boiling Point ]:
308.2ºC at 760mmHg

[ Molecular Formula ]:
C9H8O4

[ Molecular Weight ]:
180.15700

[ Flash Point ]:
124.8ºC

[ Exact Mass ]:
180.04200

[ PSA ]:
63.60000

[ LogP ]:
1.02580

[ Vapour Pressure ]:
0.000381mmHg at 25°C

[ Index of Refraction ]:
1.633

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NT2005000
CHEMICAL NAME :
Isophthaldehyde, 4-hydroxy-5-methoxy-
CAS REGISTRY NUMBER :
2931-90-0
BEILSTEIN REFERENCE NO. :
1955742
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H8-O4
MOLECULAR WEIGHT :
180.17
WISWESSER LINE NOTATION :
VHR BQ EVH CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2960 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 198,194,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 12,42,1954
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 236,2549,1953

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(3-chloro-4-methyl-phenyl)-N-[(2,4-dimethoxyphenyl)methylideneamino]butanediamide
  • 3-ALLYL-4-HYDROXY-5-METHOXY-BENZALDEHYDE
  • 2-Hydroxy-3-methoxy-5-methylbenzaldehyde
  • Aminoform
  • Vanillin
  • 3-[(DIMETHYLAMINO)METHYL]-4-HYDROXY-5-METHOXYBENZENECARBALDEHYDE
  • 5-methoxy-m-xylene-4,alpha,alpha'-triol
  • 3-Methoxysalicylaldehyde
  • Guaiacol
  • 4-nitrosotoluene

DownStream

  • 3,4-Dihydroxy-5-methoxybenzaldehyde
  • 1,5-bis(12-bromododecyl)-2,3-dimethoxybenzene
  • 12-[3-(12-hydroxydodecyl)-4,5-dimethoxyphenyl]dodecan-1-ol
  • 5-methoxy-m-xylene-4,alpha,alpha'-triol
  • 3-Methoxy-5-nitrosalicylaldehyde
  • 4-hydroxy-5-methoxybenzene-1,3-dicarboxylic acid
  • 2-methoxy-4,6-dimethylphenol
  • 4,5-dihydroxybenzene-1,3-dicarboxylic acid
  • 6-Methoxy-2,4-dinitrophenol

Related Compounds

  • 1,3-Benzenedicarboxaldehyde,4-hydroxy-5-methoxy-,dioxime
  • 1,3-Benzenedicarboxaldehyde, 4-hydroxy-5-(1-methylethyl)
  • 4-Hydroxy-5-nitroisophthalaldehyde
  • 1,3-BENZENEDICARBOXALDEHYDE, 4-HYDROXY-6-METHOXY-
  • 1,3-Benzenedicarboxaldehyde,2-bromo-4-hydroxy-5,6-dimethoxy-
  • 1-(3,4-dichloro-phenyl)-3-hydroxy-5-methoxy-4,4-dimethyl-imidazolidin-2-one