Ro 90-7501

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Names

[ CAS No. ]:
293762-45-5

[ Name ]:
Ro 90-7501

[Synonym ]:
Ro 90-7501
2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
GNF-Pf-5510

Chemical & Physical Properties

[ Density]:
1.443g/cm3

[ Boiling Point ]:
751.035ºC at 760 mmHg

[ Molecular Formula ]:
C20H16N6

[ Molecular Weight ]:
340.38100

[ Flash Point ]:
449.122ºC

[ Exact Mass ]:
340.14400

[ PSA ]:
109.40000

[ LogP ]:
5.10000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.842

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.

J. Struct. Biol. 130 , 232-246, (2000)

Assemblyof the amyloid-beta peptide (Abeta) into fibrils and its deposition in distinct brain areas is considered responsible for the pathogenesis of Alzheimer's disease (AD). Thus, inhibition of fibr...

Protein aggregation and neurodegenerative disease.

Nat. Med. 10 Suppl , S10-S17 , (2004)

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases are increasingly being realized...


More Articles

Related Compounds

  • 3-Acetyloxindole
  • RO 28-2653
  • Ro 44-3888
  • RO 5263397
  • Ro 67-7476
  • Ro 25-6981 hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • (3-Fluoro-8-azabicyclo[3.2.1]octan-3-yl)methanol hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-cyclopentyl-2-phenyl-N-(2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)ethyl)thiazole-4-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-((3-Amino-5-(aminomethyl)-2-methyl-4-pyridyl)methyl)-2-thiopseudourea trihydrobromide
  • (1H-indol-5-yl)(5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone