(±)-Norcantharidin
Suppliers
Names
[ CAS No. ]:
29745-04-8
[ Name ]:
(±)-Norcantharidin
[Synonym ]:
(1R,2S,6R,7S)-4,10-Dioxatricyclo[5.2.1.0]decane-3,5-dione
norcantharadin
(3aR,4S,7R,7aS)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione
4,10-dioxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
exo-3,6-Epoxyhexahydrophthalic Anhydride
exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride
MFCD00213361
Isocantharidin
demethyl cantharidin
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (4R,7S)-
7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylc acid anhydride
7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylic acid anhydride
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aR,4S,7R,7aS)-
(1R,7S)-4,10-Dioxatricyclo[5.2.1.0]decane-3,5-dione
endothallanhydride
Norcantharidin
exo,exo-4,10-dioxatricyclo[5.2.1.02.6]decane-3,5-dione
Exo-7-oxabicyclo(2.2.1)h
(4R,7S)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
362.5±35.0 °C at 760 mmHg
[ Melting Point ]:
114-116ºC
[ Molecular Formula ]:
C8H8O4
[ Molecular Weight ]:
168.147
[ Flash Point ]:
167.0±26.0 °C
[ Exact Mass ]:
168.042252
[ PSA ]:
52.60000
[ LogP ]:
-0.85
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.550
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RN8400000
- CHEMICAL NAME :
- 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, exo-
- CAS REGISTRY NUMBER :
- 29745-04-8
- BEILSTEIN REFERENCE NO. :
- 0084287
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H8-O4
- MOLECULAR WEIGHT :
- 168.16
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 35,823,1987
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
RN8400000
[ HS Code ]:
2932999099
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932999099
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Asian Nat. Prod. Res. 17 , 800-7, (2015)
Two new triterpenoid saponins, oleiferoside N and oleiferoside O, were isolated from the EtOH extract from the roots of Camellia oleifera C. Abel. Their structures were elucidated as 16α-acetoxy-21β,2...
Sci. Rep. 5 , 11836, (2015)
Cantharidin is an active constituent of mylabris, a traditional Chinese medicine, and is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays an important role in cell cycle co...
Biochem. Biophys. Res. Commun. 447(2) , 371-7, (2014)
Graphical abstract