Silidianin

Suppliers

Names

[ Name ]:
Silidianin

[Synonym ]:
Silidianin
Silydianin
(1R,3R,6R,7R,10R)-3-Hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-[(2R,3R)-3,5,7-trihydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]-4-oxatricyclo[4.3.1.0]dec-8-en-2-one
Silydianin (20 mg)
Silychristin
3,6-Methanobenzofuran-7(6H)-one, 4-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-4-oxo-2H-1-benzopyran-2-yl]-2,3,3a,7a-tetrahydro-7a-hydroxy-8-(4-hydroxy-3-methoxyphenyl)-, (3R,3aR,6R,7aR,8R)-

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
819.0±65.0 °C at 760 mmHg

[ Melting Point ]:
191 °C

[ Molecular Formula ]:
C₂₅H₂₂O₁₀

[ Molecular Weight ]:
482.436

[ Flash Point ]:
285.0±27.8 °C

[ Exact Mass ]:
482.121307

[ PSA ]:
162.98000

[ LogP ]:
1.84

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.747

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
22-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes.

Pharmacol. Res. 25(2) , 147-54, (1992)

The effect of several flavanolignans (silicristin, silidianin, silybin and isosilybin) present in silymarin, the extract of Silybum marianum fruits, was tested on lipid peroxidation in rat liver micro...

[Silymarin in the treatment of chronic liver diseases: past and future].

Orv. Hetil. 149(51) , 2413-8, (2008)

In the treatment of chronic liver diseases adequate therapy can be chosen only in the knowledge of pathogenetic processes. In the liver diseases caused by oxidative stress (alcoholic and non-alcoholic...

Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.

J. Chromatogr. A. 1116(1-2) , 57-68, (2006)

A selective and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed for the characterization of silymarin in commercially available milk thistle extract. In t...

2-(Aminomethyl)-4-(difluoromethyl)pyridine-6-sulfonamide
2-(Difluoromethyl)naphthalene-6-acetonitrile
2-(Difluoromethoxy)-5-(perfluorophenyl)pyrimidine
5-Iodo-2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine
[1-(5-Iodopyrimidin-2-yl)piperidin-4-yl]methanol
N-(1-Ethyl-1H-pyrazol-4-yl)-5-iodo-2-pyrimidinamine
5-iodo-N-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)pyrimidin-2-amine
2-(Difluoromethyl)-6-hydroxy-5-iodopyridine-3-methanol
2-Ethoxy-2-(oxan-3-yl)acetic acid
2-(Difluoromethyl)-5-methoxy-4-methylpyridine-3-carboxylic acid

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