2,2-bis(4-chlorophenoxy)acetic acid

Names

[ CAS No. ]:
29815-94-9

[ Name ]:
2,2-bis(4-chlorophenoxy)acetic acid

[Synonym ]:
Acetic acid,bis(4-chlorophenoxy)
bis(4-chlorophenoxy)acetic acid
Bis-(4-chlorphenoxy)-essigsaeure
Bis-(p-chlorophenoxy)-essigsaeure
ACETIC ACID,BIS(p-CHLOROPHENOXY)
Bis(p-chlorophenoxy)acetic acid
EINECS 249-874-7
MFCD00004227
Refortan

Chemical & Physical Properties

[ Density]:
1.441g/cm3

[ Boiling Point ]:
464ºC at 760 mmHg

[ Melting Point ]:
138-140ºC(lit.)

[ Molecular Formula ]:
C14H10Cl2O4

[ Molecular Weight ]:
313.13300

[ Flash Point ]:
234.4ºC

[ Exact Mass ]:
311.99600

[ PSA ]:
55.76000

[ LogP ]:
3.86190

[ Vapour Pressure ]:
2.08E-09mmHg at 25°C

[ Index of Refraction ]:
1.608

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AF5470000
CHEMICAL NAME :
Acetic acid, bis(p-chlorophenoxy)-
CAS REGISTRY NUMBER :
29815-94-9
BEILSTEIN REFERENCE NO. :
1887740
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H10-Cl2-O4
MOLECULAR WEIGHT :
313.14
WISWESSER LINE NOTATION :
GR DOYVQOR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
555 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,211,1970

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
AF5470000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Dichloroacetic acid
  • 4-Chlorophenol

DownStream

  • 2,2-bis(4-chlorophenoxy)-N-(2-hydroxyethyl)acetamide
  • Urefibrate

Articles

[Impact of infusion therapy on the indices of endogenous intoxication in severe combined trauma of the abdominal organs].

Klin. Khir. (2) , 67-70, (2013)

The peculiarities of course of endogenous intoxication (EI) in severe combined abdominal trauma were studied up in experiment. There was established, that in the laboratory animals, to whom the blood ...

[Using solutions of hydroxyethyl starch (6% HES 200/0.5 (refortan) and 6% HES 130/0.4 (voluven)) in neuroanesthesiology].

Anesteziol. Reanimatol. (2) , 27-30, (2008)

The paper provides the results of a complex experimental and clinical study of the effects of infusion solutions of hydroxyethyl starch (HES 200/0.5--Refortan and HES 130/0.4--Voluven) on hemostatic a...

[Experience with using of solutions of hydroxyethyl starch (refortan and voluven) in neuroanesthesiology].

Vestn. Khir. Im. I. I. Grek. 166(6) , 56-60, (2007)

The investigation has shown that solutions of hydroxyethyl starch included in complex infusion therapy facilitate stabilization of hemodynamics in neurosurgical patients during surgery. Refortan exert...


More Articles

Related Compounds

  • 2-(3,5-dihydro-2H-1,4-thiazepin-4-yl)ethyl 2,2-bis(4-chlorophenoxy)acetate
  • ()-(1-methylpyrrolidin-2-yl)methyl bis(4-chlorophenoxy)acetate hydrochloride
  • (+)-(1-methylpyrrolidin-2-yl)methyl bis(4-chlorophenoxy)acetate hydrochloride
  • 2,2-bis(4-hydroxyphenyl)acetic acid
  • 2,2-bis(4-iodophenyl)acetic acid
  • 2,2-bis(4-methoxyphenyl)acetic acid