H-Gly-Sar-OH

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Names

[ CAS No. ]:
29816-01-1

[ Name ]:
H-Gly-Sar-OH

[Synonym ]:
2-(2-Amino-N-methylacetamido)acetic acid
N-glycyl-sarcosine
MFCD00038193
Glycylsarcosine
Glycyl-sarcosine
H-Gly-Sar-OH
Gly-Sarcosin
Gly-Sar
EINECS 249-875-2

Chemical & Physical Properties

[ Density]:
1.284g/cm3

[ Boiling Point ]:
333.5ºC at 760mmHg

[ Melting Point ]:
198-202 °C (dec.)

[ Molecular Formula ]:
C5H10N2O3

[ Molecular Weight ]:
146.14400

[ Flash Point ]:
155.5ºC

[ Exact Mass ]:
146.06900

[ PSA ]:
83.63000

[ Vapour Pressure ]:
2.6E-05mmHg at 25°C

[ Index of Refraction ]:
1.51

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-[(2-Chloroacetyl)(methyl)amino]acetic acid
  • Z-Gly-Sar-OH

DownStream

  • 2-(2-((tert-Butoxycarbonyl)amino)-N-methylacetamido)acetic acid
  • Cyanamide, (3,4,5,6-tetrahydro-4-methyl-5-oxopyrazinyl)- (9CI)
  • 1-methylpiperazine-2,5-dione

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

QSAR-based permeability model for drug-like compounds.

Bioorg. Med. Chem. 19 , 2615-24, (2011)

A QSAR model was developed for predicting intestinal drug permeability, one of the most important parameters when evaluating compounds in drug discovery projects. First, a set of relevant properties f...

Intestinal absorption mechanisms of MTBH, a novel hesperetin derivative, in Caco-2 cells, and potential involvement of monocarboxylate transporter 1 and multidrug resistance protein 2.

Eur. J. Pharm. Sci. 78 , 214-24, (2015)

Hesperetin, the aglycone of hesperidin, occurs naturally in citrus fruits. It exerts extensive pharmacological activities. However, hesperetin's poor solubility and low bioavailability limit its wide ...

Mechanistic insights into PEPT1-mediated transport of a novel antiepileptic, NP-647.

Mol. Pharm. 9(9) , 2458-68, (2012)

The present study, in general, is aimed to uncover the properties of the transport mechanism or mechanisms responsible for the uptake of NP-647 into Caco-2 cells and, in particular, to understand whet...


More Articles

Related Compounds

  • H-Gly-Sar-Sar-OH
  • H-Gly-Gly-Sar-OH
  • Z-Gly-Sar-OH
  • Boc-Ala-Gly-Sar-OH
  • Glycine
  • Sarcosine
  • 4-(Difluoromethyl)-5-fluoro-3-methoxypicolinaldehyde
  • 2-(4-(Difluoromethyl)-5-hydroxy-2-(trifluoromethyl)pyridin-3-yl)acetic acid
  • 4-(Difluoromethyl)-2-hydroxy-6-methoxypyridine-3-sulfonamide
  • 2-(4-(Difluoromethyl)-5-nitro-2-(trifluoromethoxy)pyridin-3-yl)acetic acid
  • 4-(Difluoromethyl)-6-fluoro-2-methoxypyridine-3-sulfonamide
  • 4-(Difluoromethoxy)-3-phenyl-1H-pyrrolo[2,3-b]pyridine
  • 4-(Difluoromethyl)-6-(hydroxymethyl)-5-methylpyridin-3-ol
  • 4-(Difluoromethyl)-6-iodo-5-methoxypyridine-2-sulfonamide
  • (4-(Difluoromethyl)-2-iodo-5-(trifluoromethyl)pyridin-3-yl)methanol
  • 4-(Difluoromethyl)-6-hydroxy-2-iodopyridine-3-sulfonamide