Calcium gluconate
Suppliers
Names
[ CAS No. ]:
299-28-5
[ Name ]:
Calcium gluconate
[Synonym ]:
Calcium gluconate
D-Gluconic acid,calcium salt
D-Gluconsaeure,Calciumgluconat
EINECS 206-075-8
calglucol
calcicol
Calcium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
Calcium di(D-gluconate)
dragocal
Gluconic acid, calcium salt, D-
Calcisan
calcipur
CalciuM Gluconate Monohydrate
novocal
D-gluconic acid,calcium-D gluconate
calcium bis(D-gluconate)
D-Gluconic acid, calcium salt (2:1)
Gluconic Acid Calcium Salt Monohydrate
ebucin
kalpren
D-Gluconic acid calcium salt
2,3,4,5,6-Pentahydroxycaproic Acid hemicalcium salt,Gluconic acid hemicalcium salt
CALCIUM D-GLUCONATE
D-Gluconsaeure,Calcium-D-gluconat
Gluconic acid, calcium salt (2:1), D-
glucal
Calciumbis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoat]
gluconic acid calcium salt
Ca-D-gluconate
Bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate] de calcium
MFCD00064209
Calcium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate] (non-preferred name)
Biocal
Gluconate (Calcium)
Chemical & Physical Properties
[ Boiling Point ]:
673.6ºC at 760 mmHg
[ Melting Point ]:
195°C
[ Molecular Formula ]:
C6H12O7.1/2Ca
[ Molecular Weight ]:
216.20
[ Flash Point ]:
375.2ºC
[ PSA ]:
254.90000
[ Water Solubility ]:
3.3 g/100mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EW2100000
- CHEMICAL NAME :
- Calcium gluconate
- CAS REGISTRY NUMBER :
- 299-28-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C12-H22-O14.Ca
- MOLECULAR WEIGHT :
- 430.42
- WISWESSER LINE NOTATION :
- QVYQYQYQYQ1Q 2 &-CA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 143 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 129,347,1945
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Brain and Coverings - meningeal changes Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 129,347,1945
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 26,144,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 950 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,226,1982
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 26,144,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969- Volume(issue)/page/year: 15(1-2),121,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2890 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,47,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 950 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,492,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1987 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,183,1933
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1810 mg/kg
- TOXIC EFFECTS :
- Cardiac - other changes Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 191,44,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80373 No. of Facilities: 267 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 14905 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80373 No. of Facilities: 565 (estimated) No. of Industries: 3 No. of Occupations: 16 No. of Employees: 29060 (estimated) No. of Female Employees: 23111 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-36/37/38
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
EW2100000
[ HS Code ]:
2918160000
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918160000
[ Summary ]:
2918160000. gluconic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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