P7C3

Suppliers

Names

[ Name ]:
P7C3

[Synonym ]:
P7C3
1-(3,6-Dibromo-carbazol-9-yl)-3-phenylamino-propan-2-ol
1-Anilino-3-(3,6-dibromo-9H-carbazol-9-yl)-2-propanol
9H-Carbazole-9-ethanol, 3,6-dibromo-α-[(phenylamino)methyl]-
1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol
1-Anilino-3-(3,6-dibromo-9H-carbazol-9-yl)propan-2-ol

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
656.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₈Br₂N₂O

[ Molecular Weight ]:
474.188

[ Flash Point ]:
350.8±31.5 °C

[ Exact Mass ]:
471.978577

[ PSA ]:
37.19000

[ LogP ]:
6.60

[ Appearance of Characters ]:
white solid

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.687

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H318

[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected].

Neurosci. Lett. 591 , 86-92, (2015)

Down syndrome (DS) is the most common genetic cause of intellectual disability and developmental delay. In addition to cognitive dysfunction, DS patients are marked by diminished neurogenesis, a neuro...

Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies.

Hum. Mol. Genet. 22(7) , 1432-42, (2013)

Retinal dystrophies are predominantly caused by mutations affecting the visual phototransduction system and cilia, with few genes identified that function to maintain photoreceptor survival. We reason...

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.

Proc. Natl. Acad. Sci. U. S. A. 109(42) , 17016-21, (2012)

We previously reported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective properties in newborn neural precursor cells of the hippocampal dentate gyrus. We have f...

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