N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

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Names

[ CAS No. ]:
302964-08-5

[ Name ]:
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

[Synonym ]:
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-1,3-thiazole-5-carboxamide
2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-
T6N CNJ B1 DG FM- BT5N CSJ DVMR BG F1
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
Dasatinib Impurity 4

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
333-335°C

[ Molecular Formula ]:
C16H13Cl2N5OS

[ Molecular Weight ]:
394.278

[ Exact Mass ]:
393.021790

[ PSA ]:
108.04000

[ LogP ]:
4.17

[ Index of Refraction ]:
1.717

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,6-Dichloro-2-methylpyrimidine
  • 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • 1-(6-chloro-2-methylpyrimidin-4-yl)thiourea
  • N-(4-Methoxybenzyl)-2-(6-chloro-2-MethylpyriMidin-4-ylaMino)-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide
  • 2-CHLORO-6-METHYLPHENYL ISOCYANATE
  • 2-CHLORO-N-(2-CHLORO-6-METHYLPHENYL)THIAZOLE-5-CARBOXAMIDE
  • N-(4-Methoxybenzyl)-2-chloro-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide
  • 2-Chloro-6-methylaniline
  • Carbamic acid, [5-[[(2-chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]-, 1,1-dimethylethyl ester
  • 6-Chloro-2-methylpyrimidin-4-amine

DownStream

  • Dasatinib monohydrate
  • Dasatinib (BMS-354825)
  • N-Deshydroxyethyl Dasatinib
  • Dasatinib Dimeric Impurity
  • Dasatinib Carboxylic Acid Ethyl Ester

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 3-(2,2-Difluoroethoxy)azetidine
  • 3-(But-2-EN-1-yloxy)azetidine
  • 3-[(2-Chloroprop-2-en-1-yl)oxy]azetidine
  • 3-[(Azetidin-3-yloxy)methyl]-4-fluorobenzonitrile
  • 3-[(2,5-Difluorophenyl)methoxy]azetidine
  • (2R)-2-acetamido-3-(naphthalen-1-yl)propanoic acid
  • 3-[(4-Ethylphenyl)methoxy]azetidine
  • 2-(azetidin-3-yloxy)-N-(pentan-2-yl)acetamide
  • Tert-butyl 4-(5-chloroindolin-1-yl)piperidine-1-carboxylate
  • 2-(azetidin-3-yloxy)-N-(1-methoxypropan-2-yl)acetamide
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