Depramine
Suppliers
Names
[ CAS No. ]:
303-54-8
[ Name ]:
Depramine
[Synonym ]:
(3-dibenzo[b,f]azepin-5-yl-propyl)-dimethyl-amine
Depramine
Depramina [INN-Spanish]
5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine
10,11-Dehydroimipramine
5H-Dibenz(b,f)azepine,5-(3-(dimethylamino)propyl)
Depraminum [INN-Latin]
5-(8-Dimethylaminopropyl)-iminostilben
Balipramine
5-(3'-Dimethyl-amino-propyl)-5H-dibenz<b,f>azepin
Chemical & Physical Properties
[ Density]:
1.06g/cm3
[ Boiling Point ]:
413.9ºC at 760mmHg
[ Molecular Formula ]:
C19H22N2
[ Molecular Weight ]:
278.39
[ Flash Point ]:
185.9ºC
[ Exact Mass ]:
278.17800
[ PSA ]:
6.48000
[ LogP ]:
4.32520
[ Index of Refraction ]:
1.589
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HO1480000
- CHEMICAL NAME :
- 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-
- CAS REGISTRY NUMBER :
- 303-54-8
- BEILSTEIN REFERENCE NO. :
- 1319717
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H22-N2
- MOLECULAR WEIGHT :
- 278.43
- WISWESSER LINE NOTATION :
- T C676 BNJ B3N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 41 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%