Aica ribonucleotide

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Names

[ CAS No. ]:
3031-94-5

[ Name ]:
Aica ribonucleotide

[Synonym ]:
EINECS 221-212-1
MFCD00057264
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-β-D-RIBOFURANOSYL 5'-MONOPHOSPHATE

Chemical & Physical Properties

[ Density]:
2.3g/cm3

[ Boiling Point ]:
845.3ºC at 760 mmHg

[ Melting Point ]:
198-202ºC dec.

[ Molecular Formula ]:
C9H15N4O8P

[ Molecular Weight ]:
338.21

[ Flash Point ]:
465ºC

[ Exact Mass ]:
338.06300

[ PSA ]:
213.19000

[ Index of Refraction ]:
1.831

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Acadesine (AICAR)
  • 5-Amino-4-imidazolecarboxamide
  • 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE

DownStream

Articles

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.

Br. J. Cancer 111(8) , 1562-71, (2014)

The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial effects, including a reduction in cancer risk.We investi...

Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase.

Biochemistry 52(37) , 6559-67, (2013)

N(5)-CAIR synthetase, an essential enzyme in microorganisms, converts 5-aminoimidazole ribonucleotide (AIR) and bicarbonate to N(5)-CAIR with the aid of ATP. Previous X-ray crystallographic analyses o...

Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.

PLoS ONE 7(12) , e53101, (2012)

Genistein, the major isoflavone in soybean, was recently reported to exert beneficial effects in metabolic disorders and inflammatory diseases. In the present study, we investigated the effects and me...


More Articles

Related Compounds

  • 4-amino-1H-imidazole-5-carboxamide,hydrochloride
  • 9-N-ribofuranosyluric acid 5'-monophosphate
  • 6-chloropurine riboside-5'-o-monophosphate sodium salt
  • Acadesine (AICAR)
  • [(2R,3S,4R,5R)-3,4-dihydroxy-5-[(2-sulfanylacetyl)amino]oxolan-2-yl]methyl dihydrogen phosphate
  • 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]imidazole-4-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • [1-(3,3-Dimethylpentyl)azetidin-2-yl]methanamine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-[2-(2-Methoxyphenyl)ethynyl]pyrrolidine
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-(6-{[(benzyloxy)carbonyl]amino}-9H-purin-9-yl)propanoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde