2-(Trifluoromethyl)phenylacetic acid

Suppliers

Names

[ CAS No. ]:
3038-48-0

[ Name ]:
2-(Trifluoromethyl)phenylacetic acid

[Synonym ]:
ortho-(trifluoromethyl)phenylacetic acid
EINECS 207-093-9
2-(Trifluoromethyl)benzeneacetic acid
QV1R BXFFF
2-(2'-trifluoromethylphenyl)acetic acid
2-[2-(Trifluoromethyl)phenyl]acetic acid
2-(Trifluoromethyl)phenylacetic acid
MFCD00004327
[2-(Trifluoromethyl)phenyl]acetic acid
(a,a,a-trifluoro-o-tolyl)acetic acid
Benzeneacetic acid, 2-(trifluoromethyl)-
(α,α,α-Trifluoro-o-tolyl)acetic acid
o-(Trifluoromethyl)phenylacetic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
249.9±35.0 °C at 760 mmHg

[ Melting Point ]:
107-110 °C(lit.)

[ Molecular Formula ]:
C9H7F3O2

[ Molecular Weight ]:
204.146

[ Flash Point ]:
105.0±25.9 °C

[ Exact Mass ]:
204.039810

[ PSA ]:
37.30000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.475

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Precursor & DownStream

Precursor

  • 1-(pyrrolidin-1-yl)-2-(2-(trifluoromethyl)phenyl)ethan-1-one
  • 2-(Trifluoromethyl)benzaldehyde
  • 1-(2,2-dibromovinyl)-2-(trifluoromethyl)benzene
  • (2-(Trifluoromethyl)phenyl)methanol
  • 1-(Bromomethyl)-2-(trifluoromethyl)benzene
  • (2-(trifluoromethyl)phenyl)magnesium bromide
  • 2-(Trifluoromethyl)benzyl cyanide

DownStream

  • 2-(Trifluoromethyl)benzamide
  • 2-(Trifluoromethyl)benzaldehyde
  • 1-[2-(Trifluoromethyl)phenyl]acetone
  • ethyl 2-[2-(trifluoromethyl)phenyl]acetate

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Cyclic RGD peptide analogues as antiplatelet antithrombotics.

J. Med. Chem. 35 , 2040, (1992)

Stimulation of platelets activates GPIIbIIIa, the heterodimeric integrin receptor, to bind fibrinogen (Fg), which results in platelet aggregation. GPIIbIIIa/Fg binding inhibitors are potentially suita...

Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors.

J. Med. Chem. 33 , 1892, (1990)

A series of 2,6-disubstituted 4-(2-arylethenyl)phenols with potent human neutrophil 5-lipoxygenase (5-LO) inhibiting activity (IC50S in the 10(-7) M range) and weaker human platelet cyclooxygenase (CO...


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Related Compounds

  • 4-Fluoro-2-(trifluoromethyl)phenylacetic acid
  • 5-Fluoro-2-(trifluoromethyl)phenylacetic acid
  • 5-Chloro-2-(trifluoromethyl)phenylacetic acid
  • 5-Methyl-2-(trifluoromethyl)phenylacetic acid
  • 5-Methoxy-2-(trifluoromethyl)phenylacetic acid
  • 4-Methoxy-2-(trifluoromethyl)phenylacetic acid
  • Potassium ([1,1'-biphenyl]-4-ylethynyl)trifluoroborate
  • Chloromethyl 2-{[(tert-butoxy)carbonyl]amino}-4-cyclopropyl-1,3-oxazole-5-carboxylate
  • Rel-1-(tert-butyl) 3-methyl (3R,4R)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolidine-1,3-dicarboxylate
  • (R)-2-(2-Chloro-5-methoxyphenyl)-2-(methylamino)ethan-1-ol
  • Methyl (R)-3-amino-3-(4-fluoro-2-hydroxyphenyl)propanoate
  • ((3-(Hydroxymethyl)benzyl)imino)dimethyl-l6-sulfanone
  • Lithium hexafluorophosphate(V) in EC:DEC with VC
  • (S)-8-Phenyl-9a-(m-tolyl)-9,9a-dihydropyrido[1,2-a]indole-6,10-dione
  • 1-tert-butyl 4-chloromethyl (2R,4r,6S)-2,6-dimethylpiperidine-1,4-dicarboxylate
  • (R)-1-(3-Fluoro-4-methoxyphenyl)but-3-en-1-amine
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