2-Isopropyl-1H-isoindole-1,3(2H)-dione

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Names

[ CAS No. ]:
304-17-6

[ Name ]:
2-Isopropyl-1H-isoindole-1,3(2H)-dione

[Synonym ]:
N-isopropyl-phthalimide
MFCD00014582
n-isopropilftalimmide
n-isopropyl-phthalimid
PP-30
1H-Isoindole-1,3(2H)-dione, 2-(1-methylethyl)-
2-Isopropyl-isoindole-1,3-dione
ISOPROPYLPHTHALIMIDE
n-isopropylftalimid
2-Isopropylisoindoline-1,3-dione
EINECS 206-150-5
2-Isopropyl-1H-isoindole-1,3(2H)-dione

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
287.2±9.0 °C at 760 mmHg

[ Melting Point ]:
82-84ºC

[ Molecular Formula ]:
C11H11NO2

[ Molecular Weight ]:
189.210

[ Flash Point ]:
121.1±11.1 °C

[ Exact Mass ]:
189.078979

[ PSA ]:
37.38000

[ LogP ]:
2.43

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.580

MSDS

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Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5425000
CHEMICAL NAME :
Phthalimide, N-isopropyl-
CAS REGISTRY NUMBER :
304-17-6
BEILSTEIN REFERENCE NO. :
0148021
LAST UPDATED :
199803
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H11-N-O2
MOLECULAR WEIGHT :
189.23
WISWESSER LINE NOTATION :
T56 BVNVJ CY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,27,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 20,3,1965

Synthetic Route

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Precursor & DownStream

Precursor

  • Phthalic anhydride
  • isopropylamine
  • 2-Bromopropane
  • N-Benzoylisopropylamine
  • carbon monoxide
  • Isopropyl isocyanide
  • Carbon dioxide
  • 2-trimethylsilylphenyl triflate
  • Isopropanol

DownStream

  • isopropylamine

Related Compounds

  • 2-Isopropyl-5-nitro-isoindole-l,3-dione
  • 2-(Cyclopropylmethoxy)-1H-isoindole-1,3(2H)-dione
  • 2-(cyclopentyloxy)-1H-isoindole-1,3(2H)-dione
  • 2-ETHOXY-1H-ISOINDOLE-1,3(2H)-DIONE
  • 2-Mesityl-1H-isoindole-1,3(2H)-dione
  • 2-(Phenylsulfanyl)-1H-isoindole-1,3(2H)-dione