Phenazine, 5-oxide
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Names
[ CAS No. ]:
304-81-4
[ Name ]:
Phenazine, 5-oxide
[Synonym ]:
phenasine-5-oxide
phenazine mono-N-oxide
Phenazin
phenazine 5-oxide
Phenazin-5-oxid
Phenazine 9-oxide
5-oxidophenazin-5-ium
Phenazine monooxide
N-Oxyphenazine
Phenazine-N-oxide
phenazine-N5-oxide
Phenazin-5-oxide
N-Oxide de phenazine
Chemical & Physical Properties
[ Density]:
1.28g/cm3
[ Boiling Point ]:
404.3ºC at 760mmHg
[ Melting Point ]:
226.5°C
[ Molecular Formula ]:
C12H8N2O
[ Molecular Weight ]:
196.20500
[ Flash Point ]:
198.3ºC
[ Exact Mass ]:
196.06400
[ PSA ]:
38.35000
[ LogP ]:
2.81650
[ Index of Refraction ]:
1.683
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SG1590000
- CHEMICAL NAME :
- Phenazine, 5-oxide
- CAS REGISTRY NUMBER :
- 304-81-4
- BEILSTEIN REFERENCE NO. :
- 0150977
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C12-H8-N2-O
- MOLECULAR WEIGHT :
- 196.22
- WISWESSER LINE NOTATION :
- T C666 BN INJ BO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6600 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5500 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 87500 mg/kg/2Y-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10080 mg/kg/96W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 201 mg/kg
- SEX/DURATION :
- female 91 day(s) pre-mating - 21 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 201 mg/kg
- SEX/DURATION :
- multigenerations
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,185,1983
Safety Information
[ HS Code ]:
2933990019
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990019
[ Summary ]:
2933990019 phenazine 5-oxide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%