6-chloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Names

[ CAS No. ]:
30563-87-2

[ Name ]:
6-chloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

[Synonym ]:
6-chloro-TMP
6-chloro trimethoprim

Chemical & Physical Properties

[ Molecular Formula ]:
C14H17ClN4O3

[ Molecular Weight ]:
324.76300

[ Exact Mass ]:
324.09900

[ PSA ]:
106.97000

[ LogP ]:
1.77120

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-6-hydroxy-pyrimidine
  • 4,6-dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine
  • 3,4,5-Trimethoxybenzaldehyde
  • (Z)-β-(3,4,5-trimethoxyphenyl) α-cyano propenoic acid
  • 2-cyano-3-(3,4,5-trimethoxy-phenyl)propionic acid ethyl ester

DownStream

  • Trimethoprim

Related Compounds

  • 3-hydroxy-N-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-1,4-benzoxazine-6-carboxamide
  • 1-methyl-N-(2-[1,2,4]triazolo[4,3-a]pyridin-3-ylethyl)-1H-indole-5-carboxamide
  • 2-(4-chloro-1H-indol-1-yl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)acetamide
  • 1-(6-chloropyridazin-3-yl)-N-(3,4-dimethoxybenzyl)piperidine-3-carboxamide
  • 5-(3-fluorophenyl)-2-methyl-N-(2-pyridylmethyl)-1,3-thiazole-4-carboxamide
  • N-[3-(1H-benzimidazol-2-yl)propyl]-2-chloro-5-(1H-tetrazol-1-yl)benzamide
  • 3-(4-chlorophenyl)-1-methyl-N-(3-pyridylmethyl)-1H-pyrazole-5-carboxamide
  • 1-(6-chloropyridazin-3-yl)-N-(2,2-dimethyltetrahydro-2H-pyran-4-yl)piperidine-3-carboxamide
  • 1-(4,6-dimethylpyrimidin-2-yl)-N-[3-(2-methoxyphenyl)-1H-1,2,4-triazol-5-yl]piperidine-3-carboxamide
  • ethyl 2-({[3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]carbonyl}amino)-1,3-thiazole-4-carboxylate
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