1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone

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Names

[ CAS No. ]:
30652-12-1

[ Name ]:
1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone

[Synonym ]:
1-ethyl-3-hydroxy-2-methylpyridin-4-one

Chemical & Physical Properties

[ Density]:
1.168g/cm3

[ Boiling Point ]:
249.5ºC at 760 mmHg

[ Molecular Formula ]:
C8H11NO2

[ Molecular Weight ]:
153.17800

[ Flash Point ]:
104.7ºC

[ Exact Mass ]:
153.07900

[ PSA ]:
42.23000

[ LogP ]:
0.88220

[ Index of Refraction ]:
1.546

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7786040
CHEMICAL NAME :
4(1H)-Pyridinone, 1-ethyl-3-hydroxy-2-methyl-
CAS REGISTRY NUMBER :
30652-12-1
BEILSTEIN REFERENCE NO. :
1449942
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H11-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RSUSBS Resuscitation. (Elsevier/North-Holland Biomedical Press, POB 85, Limerick, Ireland) V.1- 1972- Volume(issue)/page/year: 22,139,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
815 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 76,2389,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
52 gm/kg/52W-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight Related to Chronic Data - death
REFERENCE :
MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 28(Suppl A),81,1992
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12 gm/kg/12W-I
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 78,2727,1991

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-hydroxy-2-furyl)ethanone
  • Ethylamine
  • galactosyl isomaltol
  • 3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE
  • Maltol

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-benzyl-1-ethyl-3-hydroxy-2,4(1H,3H)-quinolinedione
  • 1-Ethyl-3-hydroxypyridin-2(1H)-one
  • 1-(3-Ethoxypropyl)-3-hydroxy-2-methylpyridine-4(1H)-one
  • 1-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propyl]-3-hydroxy-2-methylpyridin-4-one
  • 1-(3,4-Dichlorobenzyl)-3-[(4-fluorobenzyl)oxy]-2-methyl-4(1H)-pyridinone
  • 4(1H)-Pyridinone,3-hydroxy-2-methyl-1-[2-(1-pyrrolidinyl)ethyl]-(9CI)
  • 2-Nitro-6-(2,2,2-trifluoroacetamido)benzoic acid
  • 5-Methyl-2-[1-(2,2,2-trifluoroacetyl)azetidin-3-yl]-1,3-oxazole-4-carboxylic acid
  • 3-(6-Hydroxypyridin-3-yl)-2-(2,2,2-trifluoroacetamido)propanoic acid
  • 3-Hydroxy-3-(pyridin-3-yl)-2-(2,2,2-trifluoroacetamido)propanoic acid
  • rac-tert-butyl N-[(1R,2S)-2-bromocyclohexyl]carbamate
  • 6-methyl-4-(2,2,2-trifluoroacetyl)-4H,5H,6H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid
  • 1-{[1-(2,2,2-trifluoroacetyl)azetidin-3-yl]methyl}-1H-1,2,3-triazole-4-carboxylic acid
  • 5-methyl-4-(2,2,2-trifluoroacetyl)-4H,5H,6H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid
  • 3-methyl-7-(2,2,2-trifluoroacetyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxylic acid
  • 5-Hydroxy-7-{[(prop-2-en-1-yloxy)carbonyl]amino}pyrazolo[1,5-a]pyrimidine-2-carboxylic acid