Q2YQ1Q

Suppliers

Names

[ CAS No. ]:
3068-00-6

[ Name ]:
Q2YQ1Q

[Synonym ]:
(+/-)-butan-1,2,4-triol
2-Deoxyerythritol
triol124
1,2,4-Butanetriol
1,2,4-Butanetriol 1,2,4-Butanetriol
butane-1,2,4-triol
1,2,4-BUTANTRIOL
4-Butanetriol
Butanetriol
MFCD00002929
trihydroxybutane
1,3,4-butanetriol
(±)-1,2,4-Butanetriol (BT)
EINECS 221-323-5
Q2YQ1Q
1,2,4-trihydroxy butane

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
303.9±0.0 °C at 760 mmHg

[ Melting Point ]:
-20ºC

[ Molecular Formula ]:
C4H10O3

[ Molecular Weight ]:
106.120

[ Flash Point ]:
153.9±16.4 °C

[ Exact Mass ]:
106.062996

[ PSA ]:
60.69000

[ LogP ]:
-2.09

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.487

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK7176000
CHEMICAL NAME :
1,2,4-Butanetriol
CAS REGISTRY NUMBER :
3068-00-6
BEILSTEIN REFERENCE NO. :
1733456
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H10-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 93,152,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
EK7176000

[ HS Code ]:
2905499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (±)-Malic Acid
  • Dimethyl malate
  • oxirane-2,3-dimethanol
  • 3-Buten-1-ol
  • Dimethyl malate
  • Dimethyl malate
  • Diethyl malate
  • Sorbitol
  • gamma-Butyrolactone
  • 1,4-Dihydroxy-2-butanone

DownStream

  • 2-DEOXYERYTHRITOL
  • 2-DEOXYERYTHRITOL
  • 3-Hydroxytetrahydrofuran
  • 2-(oxiran-2-yl)ethanol
  • acetic acid,oxolan-3-ol
  • (S)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane
  • [(4S)-2,2-Dimethyl-1,3-dioxan-4-yl]methanol
  • 2-Butanol,1,4-dichloro-
  • 1,4-Butanediol

Customs

[ HS Code ]: 2905499000

[ Summary ]:
2905499000 other polyhydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters.

Cancer Chemother. Pharmacol. 75(2) , 281-91, (2015)

Despite overall successful application to multiple myeloma patients, clinical efficacy of the proteasome inhibitor bortezomib is typically challenged by primary and secondary resistance of unknown ori...

Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.

J. Mol. Biol. 427(8) , 1765-78, (2015)

The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex performs multiple functions in transcription activation including deubiquitinating histone H2B, which is mediated by a subcomplex called the deubiquit...

Evidence for a KATP Channel in Rough Endoplasmic Reticulum (rerKATP Channel) of Rat Hepatocytes.

PLoS ONE 10 , e0125798, (2015)

We report in a previous study the presence of a large conductance K+ channel in the membrane of rough endoplasmic reticulum (RER) from rat hepatocytes incorporated into lipid bilayers. Channel activit...


More Articles