Febuprol

Suppliers

Names

[ Name ]:
Febuprol

[Synonym ]:
1-Butoxy-3-phenoxy-2-propanol
1-Phenoxy-3-butoxy-2-propanol
MFCD00867165
Febuprol
2-Propanol,1-n-butoxy-3-phenoxy
3-n-Butoxy-1-phenoxy-2-propanol
2-Propanol,1-butoxy-3-phenoxy
1-phenoxy-2-hydroxy-3-butoxypropane
1-n-Butyl-3-phenyl diether glycerol
1-butoxy-3-phenoxy-propan-2-ol
Valbil
EINECS 221-454-8

Chemical & Physical Properties

[ Density]:
1.034 g/cm3

[ Boiling Point ]:
346ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₂₀O₃

[ Molecular Weight ]:
224.29600

[ Flash Point ]:
163.1ºC

[ Exact Mass ]:
224.14100

[ PSA ]:
38.69000

[ LogP ]:
2.24300

[ Index of Refraction ]:
1.502

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA8400000

CHEMICAL NAME :: 2-Propanol, 1-butoxy-3-phenoxy-

CAS REGISTRY NUMBER :: 3102-00-9

BEILSTEIN REFERENCE NO. :: 1876848

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H20-O3

MOLECULAR WEIGHT :: 224.33

WISWESSER LINE NOTATION :: 4O1YQ1OR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2370 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3050 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 436 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974

Safety Information

[ HS Code ]:
2909499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

phenyl glycidyl ether
Butanol
Terabutyl titanate

DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

2-Fluoro-5-[(1-oxo-1lambda6-thiolan-1-ylidene)amino]benzene-1-sulfonyl chloride
4-[(1-Oxothiolan-1-ylidene)amino]benzenesulfonyl chloride
Dimethyl({[3-(morpholin-4-yl)-1H-1,2,4-triazol-5-yl]methyl})amine
5-Bromo-7-(trifluoromethyl)-1H-indole-2-carboxylic acid
(2S,4R)-2-(Iodomethyl)-4-(4-methylphenyl)oxolane
2-{[Diethyl(oxo)-lambda6-sulfanylidene]amino}benzene-1-sulfonyl chloride
1-[(3-Methyl-4-nitrophenyl)imino]-1lambda6-thiolan-1-one
tert-Butyl N-[2-(1,2,3,4-tetrahydroisoquinolin-5-yl)ethyl]carbamate
1-{[4-(Bromomethyl)phenyl]imino}-1lambda6-thiolan-1-one
7-Methyl-6-(trifluoromethyl)-1H-indole-2-carboxylic acid