C2 Ceramide

Suppliers

Names

[ Name ]:
C2 Ceramide

[Synonym ]:
N-Ethanoyl-D-erythro-sphingosine
MFCD00153903
N-ACETYL-D-SPHINGOSINE
D-erythro-N-acetyl-sphingosine
C14 SPHINGOID BASE
C2:0 CERAMIDE
CERAMIDE C2
N-ACETYLSPHINGOSINE
Acetamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
C2-D-ERYTHRO-CERAMIDE
ACETYL CERAMIDE
N-acetyl-sphing-4-enine
C2-ceramide
Ceramide,N-Acetylsphingosine
TOC Ceramide
N-acetyl-d-erythro-sphingosine
C2 CERAMIDE
N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]acetamide

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
532.4±50.0 °C at 760 mmHg

[ Melting Point ]:
93-96ºC

[ Molecular Formula ]:
C₂₀H₃₉NO₃

[ Molecular Weight ]:
341.529

[ Flash Point ]:
275.8±30.1 °C

[ Exact Mass ]:
341.292999

[ PSA ]:
69.56000

[ LogP ]:
5.90

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.485

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924199090

Precursor & DownStream

Precursor

D-erythro-Sphingosine
Acetyl chloride
Ethanoic anhydride
erythro-N-acetyl-1-O-benzoylsphingosine
1-Pentadecyne
erythro-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ2-oxazoline
1-O-Benzoyl-D-erythro-C18-sphingosine hydrochloride
N,1-O,3-O-Triacetylsphingosine

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2.

In Vitro Cell. Dev. Biol. Anim. 51 , 1056-63, (2015)

Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study i...

Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes.

PLoS ONE 10(4) , e0119005, (2015)

Conjugated linoleic acid (CLA) reduces adiposity in human and mouse adipocytes. This outcome is achieved through a variety of biological responses including increased energy expenditure and fatty acid...

C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.

Endocrinology 147 , 4363-73, (2006)

The stress kinase c-jun N-terminal kinase (JNK) was recently shown to be involved in the pathophysiology of major inflammatory conditions, including Alzheimer's disease, stroke, obesity, and type II d...