Benzyl 1-piperazinecarboxylate

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Names

[ CAS No. ]:
31166-44-6

[ Name ]:
Benzyl 1-piperazinecarboxylate

[Synonym ]:
Benzyl piperazine-1-carboxylate
Piperazine-1-carboxylic Acid Benzyl Ester
4-benzyloxycarbonylpiperazine
Benzyl 1-piperazinecarboxylate
1-Z-Piperazine
N-carbobenzyloxypiperazine
1-(Benzyloxycarbonyl)piperazine
1-Cbz-Piperazine
1-Piperazinecarboxylic acid, phenylmethyl ester
benzyl N-piperazinecarboxylate
MFCD00274317
phenylmethyl piperazinecarboxylate
1-Carbobenzoxypiperazine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
352.4±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H16N2O2

[ Molecular Weight ]:
220.27

[ Flash Point ]:
166.9±24.6 °C

[ Exact Mass ]:
220.121185

[ PSA ]:
41.57000

[ LogP ]:
1.17

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.547

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperazine
  • Benzyl chloroformate
  • Piperazine-1,4-dicarboxylic acid benzyl ester tert-butyl ester
  • Piperazine Hexahydrate
  • Phenyl chloroformate

DownStream

  • 1-CBZ-4-(2-AMINOETHYL)PIPERAZINE
  • piperazine dihydrochloride
  • BENZYL 4-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)PIPERAZINE-1-CARBOXYLATE
  • BENZYL 4-(PYRROLIDIN-3-YL)PIPERAZINE-1-CARBOXYLATE
  • benzyl 4-methylpiperazine-1-carboxylate
  • benzyl 4-(2-formylphenyl)piperazine-1-carboxylate

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis of Macrocyclic, Triazine-Based Receptor Molecules. Löwik DWPM and Lowe CR.

European J. Org. Chem. 2001(15) , 2825-39, (2001)

Novel piperazines: potent melanocortin-4 receptor antagonists with anxiolytic-like activity.

Bioorg. Med. Chem. 15(6) , 2375-85, (2007)

In the present study, we found that a novel piperazine compound, 11a, showed a moderate affinity (IC(50)=333nM) for the MC4 receptor. We developed the new type of piperazine compounds and found that m...


More Articles

Related Compounds

  • Benzyl (3S)-3-benzyl-1-piperazinecarboxylate
  • Benzyl (3R)-3-benzyl-1-piperazinecarboxylate
  • 2-Methyl-2-propanyl 2-allyl-4-benzyl-1-piperazinecarboxylate
  • (R)-1-BOC-2-BENZYLPIPERAZINE
  • tert-butyl 4-benzylpiperazine-1-carboxylate
  • (S)-1-Boc-2-benzylpiperazine
  • 6-(Sec-butyl)pyrimidin-4-ol
  • 6-((1R,2S,4R)-bicyclo[2.2.1]hept-5-en-2-yl)pyrimidin-4-ol
  • 6-(Phenoxymethyl)pyrimidin-4-ol
  • 6-(1-Phenoxyethyl)pyrimidin-4-ol
  • 6-(1-Phenylpropyl)pyrimidin-4-ol
  • 6-(3-Phenylpropyl)pyrimidin-4-ol
  • 6-(Benzo[d][1,3]dioxol-5-yl)pyrimidin-4-ol
  • 6-(Pyrazin-2-yl)pyrimidin-4-ol
  • 6-(Tetrahydrofuran-2-yl)pyrimidin-4-ol
  • 6-(3-Methylbenzyl)pyrimidin-4-ol
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