Sudan II

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Names

[ CAS No. ]:
3118-97-6

[ Name ]:
Sudan II

[Synonym ]:
Red B
EINECS 221-490-4
FAT RED
1-(2,4-Xylidylazo)-2-naphthol
AKA505
1-(2,4-Xylylazo)-2-naphthol,Solvent Orange 7
2,4-dimethyl-1-phenylazo-2-naphthol
redno.5
Rot B
SUDAN 2
1-(2',4'-dimethylbenzeneazo)-2-naphthol
1-[(2,4-dimethylphenyl)azo]-2-naphthalenol
m-Xylol-(4 azo 1)-naphthol-(2)
SUDAN
1,2-Naphthalenedione, 1-[2-(2,4-dimethylphenyl)hydrazone], (1Z)-
1-(2,4-Dimethyl-phenylazo)-[2]naphthol
MFCD00003896
Solvent Orange 7
(1Z)-1-[(2,4-Dimethylphenyl)hydrazono]-2(1H)-naphthalenone
Sudan II [=1-(2,4-Xylidylazo)-2-naphthol]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
429.6±55.0 °C at 760 mmHg

[ Melting Point ]:
156-158ºC

[ Molecular Formula ]:
C18H16N2O

[ Molecular Weight ]:
276.33

[ Flash Point ]:
213.6±31.5 °C

[ Exact Mass ]:
276.126251

[ PSA ]:
44.95000

[ LogP ]:
4.56

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.616

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL5850000
CHEMICAL NAME :
2-Naphthol, 1-(2,4-xylylazo)-
CAS REGISTRY NUMBER :
3118-97-6
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C18-H16-N2-O
MOLECULAR WEIGHT :
276.36
WISWESSER LINE NOTATION :
L66J BNUNR B1 D1& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
50 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 44,9,1977 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,233,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,233,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1408 No. of Facilities: 141 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 3517 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1408 No. of Facilities: 206 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 3262 (estimated) No. of Female Employees: 1087 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S36/37-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QL5850000

[ HS Code ]:
2927000090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-(but-2-en-1-yloxy)ethanol
  • m-Xylene
  • Naphthalen-2-amine
  • 2,4-Xylidine
  • 2-Naphthol

DownStream

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Development of a method for the analysis of seven banned azo-dyes in chilli and hot chilli food samples by pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry.

Talanta 78(1) , 178-86, (2009)

An automated, confirmatory and sensitive procedure has been developed and validated for the determination of Sudan (I-IV), Sudan Orange G, Sudan Red 7B and Para Red in hot chilli food samples. The pro...

Preparation of anti-Sudan red monoclonal antibody and development of an indirect competitive enzyme-linked immunosorbent assay for detection of Sudan red in chilli jam and chilli oil.

Analyst 135(10) , 2566-72, (2010)

Sudan dyes are banned to be used in food additives because of the carcinogenicity of their metabolites. A rapid and sensitive indirect competitive enzyme-linked immunosorbent assay (ELISA) was develop...


More Articles


Related Compounds

  • Sudan III
  • Sudan III-d6
  • Sudan II-(naphthyl-d6)
  • Sudan IV
  • Sudan I
  • sudan iv-d6
  • [1-(2-ethoxyethyl)-5-(1-methyl-1H-pyrazol-5-yl)-1H-1,2,3-triazol-4-yl]methanamine
  • 5-[(2S)-2-hydroxypropyl]-2-methoxyphenol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 14-Azido-N-(2,4-dinitrophenyl)-3,6,9,12-tetraoxatetradecan-1-amine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2,3-trimethylbutanoyl]thiomorpholine-2-carboxylic acid
  • Methyl 2-hydroxy-3-methyl-3-(5-methyl-1,2-oxazol-3-yl)butanoate